N-[(1R,3S)-3-Hydroxy-1-(hydroxymethyl)-3-phenylpropyl]dodecanamide

N-[(1R,3S)-3-Hydroxy-1-(hydroxymethyl)-3-phenylpropyl]dodecanamide 구조식 이미지
카스 번호:
383418-30-2
상품명:
N-[(1R,3S)-3-Hydroxy-1-(hydroxymethyl)-3-phenylpropyl]dodecanamide
동의어(영문):
HPA-12;N-[(2R,4S)-1,4-Dihydroxy-4-phenylbutan-2-yl]dodecanamide;N-[(1R,3S)-3-Hydroxy-1-(hydroxymethyl)-3-phenylpropyl]dodecanamide;Dodecanamide, N-[(1R,3S)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]-;N-[(1R,3S)-3-Hydroxy-1-(hydroxymethyl)-3-phenylpropyl]dodecanamide
CBNumber:
CB03069617
분자식:
C22H37NO3
포뮬러 무게:
363.53
MOL 파일:
383418-30-2.mol
MSDS 파일:
SDS

N-[(1R,3S)-3-Hydroxy-1-(hydroxymethyl)-3-phenylpropyl]dodecanamide 속성

용해도
Chloroform: soluble; DMSO: soluble
물리적 상태
powder to crystal
색상
흰색에서 거의 흰색
CAS 데이터베이스
383418-30-2

안전

HS 번호 2924.29.7790

N-[(1R,3S)-3-Hydroxy-1-(hydroxymethyl)-3-phenylpropyl]dodecanamide C화학적 특성, 용도, 생산

개요

HPA-12 is a ceramide analog and inhibitor of ceramide transfer protein (CERT). It inhibits binding of a ceramide probe to the isolated steroidogenic acute regulatory protein-related lipid transfer (START) domain of CERT with an EC50 value of 4 μM in a TR-FRET assay. HPA-12 (2.5 μM) inhibits conversion of the fluorescent ceramide analog C5-DMB-Cer to C5-DMB-sphingomyelin in CHO and HeLa cells. It also inhibits sphingomyelin synthesis in wild-type, but not ATP-dependent ceramide transport-deficient, CHO cells when used at a concentration of 1 μM.

N-[(1R,3S)-3-Hydroxy-1-(hydroxymethyl)-3-phenylpropyl]dodecanamide 준비 용품 및 원자재

원자재

준비 용품


N-[(1R,3S)-3-Hydroxy-1-(hydroxymethyl)-3-phenylpropyl]dodecanamide 공급 업체

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