데스모스테롤

데스모스테롤
데스모스테롤 구조식 이미지
카스 번호:
313-04-2
한글명:
데스모스테롤
동의어(한글):
데스모스테롤
상품명:
DESMOSTEROL
동의어(영문):
Desmostero;esmosterol;DESMOSTEROL;24-DEHYDROCHOLESTEROL;Cholesterol impurity B;desmosterol crystalline;Cholesta-5,24-dien-3-ol;5,24-Cholestadien-3β-ol;Cholesterol Impurity 12;5, 24-CHOLESTADIEN-3β-OL
CBNumber:
CB0307682
분자식:
C27H44O
포뮬러 무게:
384.65
MOL 파일:
313-04-2.mol
MSDS 파일:
SDS

데스모스테롤 속성

녹는점
121.5°, also reported as 119-119.5°
알파
D27 -41.0° (c = 1 in chloroform)
끓는 점
483.2±14.0 °C(Predicted)
밀도
1.00±0.1 g/cm3(Predicted)
저장 조건
-20°C
용해도
클로로포름(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
15.03±0.70(Predicted)
색상
흰색에서 미색까지

안전

WGK 독일 3

데스모스테롤 C화학적 특성, 용도, 생산

화학적 성질

Off-White Solid

용도

24-dehydro Cholesterol is an immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis. Structurally, it varies from cholesterol only by a single double bond at carbon 24 and has been used as cholesterol substitute in cellular membrane studies. During brain development, 24-dehydro cholesterol transiently accumulates, composing up to 30% of total brain sterol, where it is poised to rapidly enrich membrane sterols. However, defects in cholesterol synthesis can lead to a condition called, desmosterolosis, which results in an accumulation of excess 24-dehydro cholesterol. 24-dehydro Cholesterol has been reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions.[Cayman Chemical]

정의

ChEBI: A cholestanoid that is cholesta-5,24-diene substituted by a beta-hydroxy group at position 3. It is an intermediate metabolite obtained during the synthesis of cholesterol.

일반 설명

Desmosterol lacks a double bond between C24 and C25 compared to cholesterol. It is present in the membrane of spermatozoa and astrocytes and is the major brain sterol.

데스모스테롤 준비 용품 및 원자재

원자재

준비 용품


데스모스테롤 공급 업체

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Guangzhou PI PI Biotech Inc 020-81716320 +86-13602409664
Sales@pipitech.com China 3635 55

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