N-아세틸-D-글루코사민
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N-아세틸-D-글루코사민 속성
- 녹는점
- 211 °C (dec.) (lit.)
- 알파
- 42 º (c=2,water,2 hrs)
- 증기압
- 8Pa at 20℃
- 굴절률
- +39.0 to +42.0 ° (C=1, H2O)
- 저장 조건
- -20°C
- 용해도
- 진한 염산, 황산, 인산 및 포름산에 용해됩니다. 물, 묽은 산, 묽은 알칼리, 농축 알칼리 및 유기 용매에 불용성입니다.
- 물리적 상태
- 식염수 현탁액
- 끓는 점
- 636.4±55.0 °C(Predicted)
- 밀도
- 1.54 g/cm3
- 산도 계수 (pKa)
- 13.04±0.20(Predicted)
- 색상
- 흰색에서 황백색까지
- 수용성
- H2O: 50 mg/mL 무색 ~ 희미한 노란색 용액, 투명 ~ 매우 약간 흐릿한 용액
- 감도
- Hygroscopic
- Merck
- 14,4458
- BRN
- 1727589
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- InChIKey
- OVRNDRQMDRJTHS-ROGOILFBSA-N
- LogP
- -2.2 at 23.7℃
- CAS 데이터베이스
- 7512-17-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38 | ||
안전지침서 | 24/25-36-26-22 | ||
WGK 독일 | 3 | ||
RTECS 번호 | LZ6651000 | ||
F 고인화성물질 | 3-10 | ||
위험 참고 사항 | Irritant | ||
TSCA | Yes | ||
HS 번호 | 29329985 |
N-아세틸-D-글루코사민 C화학적 특성, 용도, 생산
개요
N-Acetyl-D-Glucosamine is the N-acetyl derivative of glucosamine.Chemically it is an amide between glucosamine and acetic acid. A single N-acetlyglucosamine moiety linked to serine or threonine residues on nuclear and cytoplasmic proteins -O-GlcNAc, is an ubiquitous post-translational protein modification. O-GlcNAc modified proteins are involved in sensing the nutrient status of the surrounding cellular environment and adjusting the activity of cellular proteins accordingly. O-GlcNAc regulates cellular responses to hormones such as insulin, initiates a protective response to stress, modulates a cell's capacity to grow and divide, and regulates gene transcription. In humans, it exists in skin, cartilage and blood vessel as a component of hyaluronic acid, and bone tissue, cornea and aorta as a component of keratan sulfate.N-Acetyl-D-glucosamine (D-GlcNAc) is a derivitized glucose monomer found in polymers of bacterial cell walls, chitin, hyaluronic acids and various glycans. It is also synthesized in the glycosylation pathway as uridine diphosphate (UDP-GlcNAc), which can then be released following degradation of glycosylated proteins.D-GlcNAc is used to identify, differentiate and characterize N-acetyl-β-D-hexoaminidase(s). It is also used in the treatment of osteoarthritis and inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. Further, it is used as a substrate in sialic acid production, cosmetics and in drug development research.
화학적 성질
White powder용도
N-Acetyl-D-glucosamine is used in the identification and characterization of N-acetyl-beta-D-hexoaminidase. It is also used in the treatment of osteoarthritis and inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. Further, it is used as a substrate in sialic acid production, cosmetics and in drug development research.정의
ChEBI: N-acetyl-D-glucosamine is the D isomer of N-acetylglucosamine. It has a role as a bacterial metabolite. It is a N-acetylglucosamine and a N-acetyl-D-hexosamine.일반 설명
N-Acetylglucosamine (GlcNAc) is a monosaccharide, derived from glucose and undergoes linear polymerization by (1,4)-β-linkages to form the polymer chitin. It is also a component of heterogenous polysaccharides, such as murein and hyaluronic acid. N-acetylglucosamine exhibits anti-inflammatory properties and is considered as a potential drug in the treatment of osteoarthritis. Its antiarthritic mode of mechanism involves the suppression of IL-1β (Interleuken-1β)-induced NO (nitric oxide), cyclooxygenase-2 (COX-2), and IL-6 production by inhibition of expression of iNOS (inducible nitric oxide synthase) protein and mRNA.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
N-아세틸-D-글루코사민 준비 용품 및 원자재
원자재
준비 용품
N-아세틸-D-글루코사민 공급 업체
글로벌( 683)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Anhui Yiao New Material Technology Co., Ltd | +86-199-55145978 +8619955145978 |
sales8@anhuiyiao.com | China | 253 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 |
sales@chembj.net | China | 269 | 58 |
zhuzhou dingcheng meihei comestic co.,ltd | +undefined18873369619 |
dingchengbusiness8@163.com | China | 241 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7786 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 |
sales02@airuikechemical.com | China | 994 | 58 |
Hebei Saisier Technology Co., LTD | +86-18400010335 +86-13102810335 |
admin@hbsaisier.cn | China | 690 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
N-아세틸-D-글루코사민 관련 검색:
아세트아미노펜 D-글루코사민 2,4-펜탄디온 아세틸 염화물 말토덱스트린 키틴 N-아세틸-D-글루코사민
Glucosamine
D-Glucose monohydrate
Acetoacetamide
Acesulfame potassium
L-Tyrosine
N-ACETYLMURAMIC ACID
N,N',N''-TRIACETYLCHITOTRIOSE
ACETYL-D-GLUCOSAMINE, N-[GLUCOSAMINE-1-14C]
N-ACETYLGLUCOSAMINE 6-SULFATE SODIUM SALT
N,N'-Diacetylchitobiose
SIALYL LEWIS X