KDOAM-25
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KDOAM-25 속성
- 끓는 점
- 478.6±45.0 °C(Predicted)
- 밀도
- 1.137±0.06 g/cm3(Predicted)
- 저장 조건
- -20°C
- 산도 계수 (pKa)
- 15.03±0.50(Predicted)
안전
KDOAM-25 C화학적 특성, 용도, 생산
Biochem/physiol Actions
KDOAM25 is a selective inihbitor of the KDM5 family histone demethylases JARID1A, JARID1B, JARID1C and JARID1D with IC50 values < 60 nM. JARID1A and JARID1B are independently overexpressed in some cancers with JARID1B (KDM5B, PLU1) also identified as a potential oncogene, a repressor of tumour repressor genes. JARID1C (KDM5C) and JARID1D (KDM5D) are located on the X- and Y-chromosomes respectively. KDOAM25′s closest off-target is JMJD2C (selectivity >400 fold). It shows no activity on other tested 2-OG family members, including FIH, NO66, MINA53 and PHD2. KDOAM25 is active in cells.KDOAM-25 준비 용품 및 원자재
원자재
준비 용품
KDOAM-25 공급 업체
글로벌( 13)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 |
757984502@qq.com | China | 892 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9709 | 58 |
| DC Chemicals | 021-58447131 13564518121 |
sales@dcchemicals.com | China | 9414 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 |
hongquchem@qq.com | China | 5132 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 |
3525679403@qq.com | China | 3915 | 58 |
| cjbscvictory | 13348960310 13348960310 |
3003867561@qq.com | China | 9946 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 |
3477467573@qq.com | China | 8618 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24131 | 58 |