다우노미신
|
|
다우노미신 속성
- 녹는점
- 155 °C
- 끓는 점
- 608.13°C (rough estimate)
- 밀도
- 1.3522 (rough estimate)
- 굴절률
- 1.6400 (estimate)
- 저장 조건
- Store at -20°C, protect from light
- 용해도
- ≥83.33 mg/mL in DMSO
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- pKa 4.92±0.16(H2O t=25±0.5 I=0.03) (Uncertain)
- 안정성
- 감광성
- CAS 데이터베이스
- 20830-81-3
- IARC
- 2B (Vol. 10, Sup 7) 1987
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 유엔번호(UN No.) | 3249 | ||
|---|---|---|---|
| 위험 등급 | 6.1(b) | ||
| 포장분류 | III | ||
| 유해 물질 데이터 | 20830-81-3(Hazardous Substances Data) | ||
| 독성 | LD50 in mice, rats (mg/kg): 20, 13 i.v.; 5, 8 i.p. (DiMarco, 1977) | ||
| 기존화학 물질 | KE-00105 |
| 그림문자(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 신호 어: | Warning | |||||||||||||||||||||||||||||||||||
| 유해·위험 문구: |
|
|||||||||||||||||||||||||||||||||||
| 예방조치문구: |
|
다우노미신 C화학적 특성, 용도, 생산
화학적 성질
Daunomycin is a thin red, needle-shaped material.용도
Daunorubicin hydrochloride USP (Cerubidine) is used to traet acute lymphocytic and granulocytic leukemia; lymphomas.Indications
Daunorubicin (Cerubidine) is used to treat acute leukemias, while its structural analogue, doxorubicin (Adriamycin) is extensively employed against a broad spectrum of cancers. Although the two drugs have similar pharmacological and toxicological properties, doxorubicin is more potent against most animal and human tumors and will be discussed in greater detail.정의
ChEBI: A natural product found in Actinomadura roseola.일반 설명
Anthracycline antibiotic. An anticancer agent.Safety Profile
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Human poison by ingestion. Experimental poison by subcutaneous, intravenous, and intraperitoneal routes. Experimental teratogenic and reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also DAUNOMYCIN HYDROCHLORIDE.잠재적 노출
An antibiotic. It is used as a medicine for treating cancer.운송 방법
UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1- Poisonous materials, Technical Name Required.폐기물 처리
It is inappropriate and possi- bly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quanti- ties of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceuti- cal shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste con- taining this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.다우노미신 준비 용품 및 원자재
원자재
Sky blue
streptomyces avermifilis
에리트로마이신
글루코즈
l-LEUCYL DAUNORUBICIN
DAUNOMYCINONE
7-DEOXYDAUNOMYCINONE
Epirubicin
5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-, (8S,10R)-
Daunorubicin hydrochloride
준비 용품
다우노미신 공급 업체
글로벌( 167)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10248 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |