L-xylose
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L-xylose 속성
- 녹는점
- 150-152 °C(lit.)
- 끓는 점
- 191.65°C (rough estimate)
- 밀도
- 1.525
- 굴절률
- -20 ° (C=10, H2O)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- H2O: 0.1 g/mL, 투명, 무색
- 산도 계수 (pKa)
- 12.46±0.20(Predicted)
- 물리적 상태
- 결정성 분말
- 색상
- 흰색에서 황백색까지
- optical activity
- [α]24/D 18.7°, c = 4 in H2O
- 수용성
- 거의 투명하게
- 감도
- Hygroscopic
- BRN
- 1723080
- InChIKey
- SRBFZHDQGSBBOR-VVZXFQNISA-N
- LogP
- -2.390 (est)
- CAS 데이터베이스
- 609-06-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38 | ||
안전지침서 | 24/25-36-26 | ||
WGK 독일 | 3 | ||
F 고인화성물질 | 3-10 | ||
TSCA | Yes | ||
HS 번호 | 29400000 | ||
기존화학 물질 | KE-35441 |
L-xylose C화학적 특성, 용도, 생산
화학적 성질
L-Xylose is a white fine crystalline powder. It is an aldopentose that has a molecular formula C5H10O5 and a molar mass of 150.13 g/mol. The structure of L-xylose is presented in Figure 1. The optical rotations of D- and L-xylose are α20D = -18.6° and α20D = +18.6°, respectively (Fischer and Ruff, 1900). L-Xylose can exist in open chain form, as a pyranose or as a furanose. The relative concentrations of different stereoisomers have not been specified for L-xylose. However, for D-xylose the distribution of different forms in water are: 36.5% α-pyranose, 6% β-pyranose and less than 1 % in open chain and furanose form (Pastinen, 2000). Most likely L-xylose acts similarly to its enantiomer, and thus pyranose rings are predominant.Figure 1. Structure of L-xylose A) as a Fischer projection, B) as a ball and stick model in acyclic form and C) as a ball and stick model in pyranose ring form.
용도
L-Xylose is used in the synthesis of L-Xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.정의
ChEBI: Aldehydo-L-xylose is a xylose of ring-opened form having L-configuration.주요 응용
l-Xylose is a suitable starting material for the production of L-ribonucleosides. L- Xylose can be converted into an L-ribose derivative via oxidation and reduction steps. This product is then glycosylated to give L-ribonucleosides: L-uridine, L-cytidine, L- adenosine and L-guanosine (Moyroud and Strazewski, 1999; Chelain et al., 1995).L-Xylose can also be used as a starting material for the production of polyhydroxypyrrolidines and related analogues. These compounds have many biological activities. They are shown to have anti-HIV effects, inhibit tumor growth, and also act as ?- and ?-glucosidase inhibitors, which is of relevance for the development of diabetes drugs (Behr and Guillerm, 2007).
제조 방법
L-Xylose can be produced from L-xylulose by isomerization. This can be achieved either enzymatically or chemically under alkaline conditions. The equilibrium of the reaction between D-xylose and D-xylulose in an aqueous solution has been determined at pH 6.8-7.4 and at 25 °C to be 85:15 in favor of D-xylose (Tewari et al., 1985).L-xylose 준비 용품 및 원자재
원자재
준비 용품
L-xylose 공급 업체
글로벌( 291)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Beijing Ribio Biotech Co.,Ltd | 010-62664360 +8613328773880 |
wucy@ribio.com.cn | China | 117 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 6992 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
L-xylose 관련 검색:
D-엑실로즈 D-엑실로즈 D-릭소제 L-글루코스 n-발레알데히드 글루코오스 이소메라아제 자일리톨
4''-METHYLUMBELLIFERYL-B-D-XYLOSE
4-O-(β-D-Xylopyranosyl)-D-xylose
1,3-Di-O-acetyl-2-deoxy-5-O-benzoyl-D-xylofuranose
1,2:3,5-Di-O-isopropylidene-alpha-D-xylofuranose
Forskolin
Potassium bisaccharate
FORSKOLIN, 7-DEACETYL-7-O-HEMISUCCINYL-
5-KETO-D-GLUCONIC ACID CALCIUM SALT
5-Keto-D-gluconic acid
L-GLUCONO-1,5-LACTONE
XLD AGAR