3-Aminobenzeneboronic acid hemisulfate salt
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3-Aminobenzeneboronic acid hemisulfate salt 속성
- 녹는점
- ≥300 °C
- 저장 조건
- Inert atmosphere,2-8°C
- 수용성
- 물에 용해됨
- 물리적 상태
- 결정성 분말
- 색상
- 흰색에서 약간 베이지색
- 감도
- Hygroscopic
- BRN
- 8094151
- InChIKey
- XMVGYYBQCXVVHU-UHFFFAOYSA-N
- CAS 데이터베이스
- 66472-86-4
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38 | ||
안전지침서 | 26-36-37/39 | ||
WGK 독일 | 3 | ||
F 고인화성물질 | 3-10 | ||
위험 등급 | IRRITANT | ||
HS 번호 | 29310095 |
3-Aminobenzeneboronic acid hemisulfate salt C화학적 특성, 용도, 생산
화학적 성질
White to slightly beige crystalline powder용도
3-Aminobenzeneboronic acid hemisulfate salt is a boronic acid derivative, which can be used as an intermediate in pharmaceutical synthesis. Adsorbent additive for the chromatographic separation of 3'-terminal polynucleotides from RNA.주요 응용
3-Aminophenylboronic acid hemisulfate salt is used in the synthesis of:Phenylboronic acid-functionalized inverse opal hydrogels within microfluidic flow cells for glucose sensing.
Phenylboronic acid-salicylhydroxamic acid-derived complexing reagent for protein immobilization on chromatographic support.
It can also be used in the preparation of phenylboronic acid (PBA) monolayer-modified Au electrode for the voltammetric sensing of uridine and cytidine.
제조 방법
3-Aminobenzeneboronic acid hemisulfate salt synthesis: Benzenamine, 3-bromo-N-(diphenylmethylene)- (80,0 g; 0.24 moles) was added to the cryogenic reactor along with 1.4 equivalents of triisopropyl borate and dissolved in tetrahydrofuran. The resulting solution was cooled to -80°C under an inert atmosphere and 1.35 equivalents of n-butyllithium (as a solution in n-hexane) was added maintaining the internal temperature. When complete conversion was achieved, the reaction mixture was added to a dilute mixture of sulfuric acid (1 M) and toluene. The layers were separated to obtain an aqueous solution of 3-aminophenylboronic acid hydrogen sulfate (assay yield: 85%). 3-Aminobenzeneboronic acid hemisulfate salt can be obtained by precipitating a 0.5 M aqueous solution at pH 7.2 (pH corrected with 33% aqueous NaOH) at a temperature of 0-5°C. Filtration and drying under vacuum at 40°C for 8 hours yielded 21.7 g of 3-Aminobenzeneboronic acid hemisulfate salt (0.16 moles; 66% molar yield).3-Aminobenzeneboronic acid hemisulfate salt 준비 용품 및 원자재
원자재
준비 용품
3-Aminobenzeneboronic acid hemisulfate salt 공급 업체
글로벌( 216)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 |
sale@chuangyingchem.com | CHINA | 5909 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
Wuhan Chemwish Technology Co., Ltd | 027-67849912 |
sales@chemwish.com | CHINA | 10828 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 |
1022@dideu.com | China | 3878 | 58 |
3-Aminobenzeneboronic acid hemisulfate salt 관련 검색:
4-아미노페닐 붕소산 피나콜 에스테르 3-아미노페닐 붕소산 피나콜 에스테르 B-9-페난트레닐붕산 아닐린 황산암모늄 메틸보로닉 산 페닐붕산
2-Aminophenylboronic acid
3-AMINOBENZENEBORONIC ACID, PINACOL ESTER HYDROCHLORIDE
4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)aniline hydrochloride
(2-Aminophenyl)boronic acid hydrochloride
4-AMINOPHENYLBORONIC ACID HYDROCHLORIDE
3-AMINOPHENYLBORONIC ACID HYDROCHLORIDE
(2-AMINOPHENYL)BORONIC ACID PINACOL ESTER HYDROCHLORIDE
3-Aminobenzeneboronic acid
3-Aminophenylboronic acid monohydrate
3-Aminobenzeneboronic acid hemisulfate salt
ANILINE SULFATE