디옥시니발레놀
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디옥시니발레놀 속성
- 녹는점
- 151-153 C
- 알파
- D25+6.35° (c = 0.07 in ethanol)
- 끓는 점
- 357.92°C (rough estimate)
- 밀도
- 1.48
- 굴절률
- 1.4359 (estimate)
- 인화점
- -3 °C
- 저장 조건
- -20°C
- 용해도
- DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
- 물리적 상태
- 용액(에탄올:2-프로판올 95:5)
- 산도 계수 (pKa)
- 11.91±0.70(Predicted)
- Merck
- 13,10092
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- InChI
- InChI=1/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/s3
- InChIKey
- LINOMUASTDIRTM-QUKTVYMZNA-N
- SMILES
- [C@@]12(CO1)[C@@]1([H])[C@H](O)C[C@]2(C)[C@@]2(CO)[C@H](O)C(C(C)=C[C@@]2([H])O1)=O |&1:0,3,5,8,10,13,19,r|
- LogP
- -1.250 (est)
- CAS 데이터베이스
- 51481-10-8
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T,Xn,F,Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 25-68/20/21/22-67-66-36-20/21/22-11-36/37/38 | ||
| 안전지침서 | 36/37/39-45-36-26-16-36/37-37/39 | ||
| 유엔번호(UN No.) | UN 2811 6.1/PG 2 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | YD0167000 | ||
| 위험 등급 | 6.1(a) | ||
| 포장분류 | I | ||
| HS 번호 | 29329990 | ||
| 유해 물질 데이터 | 51481-10-8(Hazardous Substances Data) | ||
| 독성 | LD50 i.p. in male, female mice (mg/kg): 70.0, 76.7 (Yoshizawa, Morooka) |
디옥시니발레놀 C화학적 특성, 용도, 생산
개요
Vomitoxin or deoxynivalenol (DON) is one of the trichothecenes (mycotoxins) which comprise a large group (148 or more have been identified) of protein synthesis inhibitors. These mycotoxins are also powerful immunosuppressants which may predispose animals to other diseases.Vomitoxin is the most commonly found trichothecene in moldy corn (maize), but a number of other biologically active trichothecenes are produced by species of the fungus Fusarium. These include nivalenol, T-2 toxin, HT-2 toxin, diacetoxyscirpenol (DAS), and monoacetoxyscipenol (MAS). These mycotoxins are most toxic when fed to swine and other monogastric animals including humans. Poultry are generally more resistant to trichothecenes than hogs, whereas T-2 toxin and DAS appear to be more toxic to chickens than vomitoxin. Toxins already present in corn at harvest may increase in stored ear corn. Extended periods of warm, rainy, or damp weather from flowering time onward promote infection of corn by Fusarium species (1–7).
화학적 성질
Off-White Solid용도
Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-κB into the nucleus.일반 설명
Deoxynivalenol belongs to the class of type B trichothecene mycotoxins typically produced by the species of Fusarium genus. It is cytotoxic and is known to hinder the macromolecular synthesis.디옥시니발레놀 준비 용품 및 원자재
원자재
준비 용품
디옥시니발레놀 공급 업체
글로벌( 153)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9641 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 |
joe@yuhengpharm.com | CHINA | 21149 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10326 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 |
ada@ipurechemical.com | CHINA | 3465 | 58 |
| Wuhan Monad Medicine Tech Co.,LTD | 02768782018 18771942761 |
sales01@whmonad.com | CHINA | 992 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 |
sales@nextpeptide.com | China | 19915 | 58 |
디옥시니발레놀 관련 검색:
디옥시니발레놀
Atropine
T-2 TOXIN
15-ACETOXY-3ALPHA,7ALPHA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-EN-8-ONE
3-ACETYL-DEOXYNIVALENOL SOLUTION (100&MU
DEOXYNIVALENOL-13C15,FULLY 13C-LABELLED DEOXYNIVALENOL
DEOXYNIVALENOL-3-GLUCOSIDE
NIVALENOL
Deepoxy-deoxynivalenol solution
DEOXYNIVALENOL 1X1ML ETOAC/MEOH(95:5)
Maize flour (deoxynivalenol, blank)
13C15 DON, Fully 13C-labelled Deoxynivalenol,Deoxynivalenol-13C15 solution
Deoxynivalenol in Maize Flour
WHEAT FLOUR - DEOXYNIVALENOL (DON)(BLANK)(CRM STANDARD)
MAIZE FLOUR - DEOXYNIVALENOL (DON)(MEDIUM LEVEL)(CRM STANDARD)
MAIZE FLOUR - DEOXYNIVALENOL (DON)(BLANK)(CRM STANDARD)
WHEAT FLOUR (DEOXYNIVALENOL MEDIUM LEVE
Wheat flour (deoxynivalenol, blank)