카테킨 C화학적 특성, 용도, 생산
존재
카테킨은 광합성에 의해 형성되는 것으로 일조량에 따라 함유량이 달라진다. 또 차의 폴리페놀 함량은 어린 찻잎보다 성숙된 찻잎에 많다. 따라서 폴리페놀은 어린잎을 가공하는 녹차보다는 성숙된 잎을 가공하는 홍차에 더 많다.
개요
카테킨은 플라보노이드 그룹의 flavan-3-ols에 속하며, 폴리페놀 일종으로 녹차의 떫은 맛 성분이다. 차류(Camellia sinensis)에서 파생되었으며, 백차, 녹차, 홍차, 우롱차에 포함되어 있다. 그러나 홍차나 우롱차의 경우 발효과정에서 반 이상의 카테킨이 줄어든다.
용도
카테킨은 발암억제, 동맥경화, 혈압상승 억제, 혈전예방, 항바이러스, 항비만, 항당뇨, 항균, 해독작용, 소염작용, 충치예방, 구갈방지, 장내 세균총 정상화 등 다양한 효과가 있다. 카테킨의 항산화 작용과 노화의 근본적 요소인 자유라디컬 제거기능은 비타민C와 비타민E에 비해 강력한 활성산소 제거효과를 가지고 있으며, 항산화작용으로 인하여 저밀도지단백(low density lipoprotein) 산화와 같은 심혈관계 보호효과가 보고되었다.
화학적 성질
Tan Solid
용도
Cianidanol, also known as (+)-catechin; (+)-3,3′4′,5,7-flavanepentol; 3,3′,4′, 5,7-pentahydroxyflavane, [R,3S]-2-[3,4-dihydroxyphenyl]-3,4-dihydro-1[2H]- benzopyran-3,4,7-triol, or 2-(3,4-dihydroxyphenyl)-3,4-dihydro-(2r-trans)-2h- 1-benzopyran-7-triol, is a flavonoid associated with a variety of blood disorders. An association of cianidanol and immune hemolytic anemia and thrombocytopenia has been suggested in numerous case reports. In several reports, the presence of flavonoid-dependent antibodies against red blood cells is evident with cianidanol combining with erythrocyte membranes and inducing development of autoantibodies and antibodies.Several patients had platelet antibodies with increased serum-bindable IgG values without the presence of cianidanol and several with high platelet-associated IgG levels.Antibodies against cianidanol were not detectable in certain cases.The hemolytic anemia caused acute renal failure in some patients and can be life threatening, leading to fatalities. Upon cessation of treatment with cianidanol, hematology appears to return to normal over time.
These side effects do not appear to be specific to cianidanol as the formation of IgE and IgG antibodies to troxerutin (Venoruton) and silymarin (Kegalon) was also evident with patients presenting with fever, skin eruptions, and intravascular hemolysis often demonstrating high IgG titers.Furthermore, cianidanol-induced hemolysis might also occur after sensitization by other flavonoids including rutin.
정의
ChEBI: The (+)-enantiomer of catechin and a polyphenolic antioxidant plant metabolite.
World Health Organization (WHO)
Cianidanol, which is extracted from the tropical plant Uncaria
gambir, was introduced in 1976 as an adjunct in the treatment of liver disorders.
Following a cluster of cases of haemolytic anaemia reported in 1985 from Naples,
Italy, four of which were fatal, the company suspended sales worldwide. Although
subsequently reintroduced in Switzerland and France for the treatment of acute
and chronic hepatitis-B, it was later definitively withdrawn in Switzerland on
detailed reassessment and the manufacturer has now withdrawn the product
worldwide.
일반 설명
(+)-Catechin is an important beneficial compound, belonging to the flavonoid class, which is present abundantly in red wine.
카테킨 준비 용품 및 원자재
원자재
준비 용품
