(RS)-(TETRAZOL-5-YL)GLYCINE
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(RS)-(TETRAZOL-5-YL)GLYCINE 속성
- 끓는 점
- 447.1±55.0 °C(Predicted)
- 밀도
- 1.804±0.06 g/cm3(Predicted)
- 저장 조건
- Store at RT
- 용해도
- DMSO: 0.25mg/mL; PBS (pH 7.2): 0.2mg/mL
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 1.04±0.10(Predicted)
- 수용성
- 물에 50mM까지 용해됨
안전
(RS)-(TETRAZOL-5-YL)GLYCINE C화학적 특성, 용도, 생산
개요
Tetrazolyl glycine is an NMDA receptor agonist. It binds to rat brain membranes with IC50 values of 98 and 36 nM for [3H]CGS19755 and [3H]glutamate, respectively, in radioligand binding assays. It induces depolarization in rat cortical slices, an effect that is blocked by the NMDA receptor antagonist LY233053. It induces degeneration of GABAergic and cholinergic neurons in the striatum of adult rats and the formation of excitotoxic lesions and seizures in neonatal rats (ED50 = 0.071 mg/kg). Intrastriatal injection of tetrazolyl glycine (5 μM) increases COX-2 expression in striatal neurons and the vasculature near the striatal injection site in a mouse model of excitotoxicity-induced neuronal injury.용도
(RS)-(Tetrazol-5-yl)glycine is a highly potent NMDA receptor agonist demonstrating ~ 20X more activity than NMDA.(RS)-(TETRAZOL-5-YL)GLYCINE 준비 용품 및 원자재
원자재
준비 용품
(RS)-(TETRAZOL-5-YL)GLYCINE 공급 업체
글로벌( 42)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 |
mike_yan@xuanranglobal.com | CHINA | 4022 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 |
sales@nextpeptide.com | China | 19915 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 |
3003855609@qq.com | China | 7892 | 56 |
| Nantong Zandery Biotechnology Co., Ltd. | 0513-87582998 13912206938 |
xiaofeizhu@vip.163.com | China | 303 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8449 | 60 |
| Shanghai QianYan Bio-technology Co., Ltd | 02781293128 |
orders@biochemsafebuy.com | China | 9934 | 55 |