Phenelzine
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Phenelzine 속성
- 녹는점
- 25°C
- 끓는 점
- bp0.1 74°
- 밀도
- 1.0348 (rough estimate)
- 굴절률
- nD20 1.5494
- 산도 계수 (pKa)
- 8.01±0.70(Predicted)
- CAS 데이터베이스
- 51-71-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
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위험 등급 | IRRITANT | ||
유해 물질 데이터 | 51-71-8(Hazardous Substances Data) | ||
독성 | LD50 oral in mouse: 130mg/kg |
그림문자(GHS): | |||||||||||||||
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신호 어: | Warning | ||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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Phenelzine C화학적 특성, 용도, 생산
개요
Monoamine oxidase inhibitors (MAOIs) were the first antidepressant drugs introduced during the 1950s. Associated with many side effects and, in particular, drug–drug and drug–food interactions, their use declined with the subsequent introduction of the tricyclic antidepressants and specific serotonin reuptake inhibitors as first-line treatments for depression.용도
Phenelzine is a MAO inhibitor which is used for treating patients with depressive characteristics such as “atypical,” “nonendogenous,” or “neurotic” conditions in which a combination of anxiety, depression, or phobia are observed. Phenelzine is not a drug of first choice, and it is used in depressions that do not respond to other medicinal drugs.Mechanism of action
Phenelzine is a hydrazine MAOI. Its mechanism of action is the prolonged, nonselective, irreversible inhibition of MAO. Phenelzine has been used with some success in the management of bulimia nervosa. The MAOIs, however, are potentially dangerous in patients with binge eating and purging behaviors, and the American Psychiatric Association states that MAOIs should be used with caution in the management of bulimia nervosa.Safety Profile
Poison by ingestion, intraperitoneal, and subcutaneous routes. Human systemic effects by ingestion: ataxia, somnolence. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Used as an antidepressant. When heated to decomposition it emits toxic fumes of NOx.환경귀착
MAOIs are available orally. Accidental or intentional ingestion are the most common routes of exposure.Phenelzine 준비 용품 및 원자재
원자재
준비 용품
Phenelzine 공급 업체
글로벌( 70)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10326 | 58 |
Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
1026@dideu.com | China | 9165 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33349 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 |
info@chemextension.com | China | 42057 | 58 |
Phenelzine 관련 검색:
인답아마이드 메타미트론
Phenelzine
MANDELIC ACID HYDRAZIDE
Phenelzine Sulfate
9-XANTHENECARBOXYLIC HYDRAZIDE
PHENYLACETIC ACID HYDRAZIDE
1-NAPHTHALENEACETHYDRAZIDE
S-(-)-Carbidopa
3,4-DIMETHOXYPHENYLACETIC ACID HYDRAZIDE
2-(3-METHOXYPHENYL)ETHANOHYDRAZIDE
BENZILIC HYDRAZIDE
PHENELZINE-D5 SULFATE,PHENELZINE-D5 SULFATE (PHENYL-D5)
SALICYLIDENE MANDELHYDRAZONE
3-AMINO-2-BENZYL-3,4-DIHYDROQUINAZOLIN-4-ONE
SPECS AN-068/40186626
3-AMINO-2-(3,4-DIMETHOXYBENZYL)-3,4-DIHYDROQUINAZOLIN-4-ONE
AURORA 4823