파미틴산 이소프로필

파미틴산 이소프로필
파미틴산 이소프로필 구조식 이미지
카스 번호:
142-91-6
한글명:
파미틴산 이소프로필
동의어(한글):
파미틴산아이소프로필;파미틴산이소프로필;이소프로필팔미테이트;아이소프로필팔미테이트;파미틴산아이소프로필
상품명:
Isopropyl palmitate
동의어(영문):
ISOPROPYL HEXADECANOATE;Deltyl;plymouthipp;ISOPROPYLPALMITAT;kesscoisopropylpalmitate;Isopal;Isopalm;Emcol-IP;estol103;ja-faipp
CBNumber:
CB0451826
분자식:
C19H38O2
포뮬러 무게:
298.5
MOL 파일:
142-91-6.mol
MSDS 파일:
SDS

파미틴산 이소프로필 속성

녹는점
11-13 °C (lit.)
끓는 점
160°C 2mm
밀도
0.852 g/mL at 25 °C (lit.)
증기압
0.007Pa at 25℃
굴절률
n20/D 1.438(lit.)
인화점
>230 °F
저장 조건
2-8°C
용해도
<0.001g/L
색상
무색
냄새
아주 가벼운 냄새
수용성
물과 섞이거나 혼합하기 어렵지 않습니다.
BRN
1786567
InChIKey
XUGNVMKQXJXZCD-UHFFFAOYSA-N
LogP
8.16
CAS 데이터베이스
142-91-6(CAS DataBase Reference)
NIST
Isopropyl palmitate(142-91-6)
EPA
Isopropyl palmitate (142-91-6)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 36/38-36/37/38
안전지침서 26-36
WGK 독일 -
RTECS 번호 RT4900000
TSCA Yes
HS 번호 29157090
유해 물질 데이터 142-91-6(Hazardous Substances Data)
독성 mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689,
기존화학 물질 KE-18449
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
예방조치문구:
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P321 (…) 처치를 하시오.
P332+P313 피부 자극이 생기면 의학적인 조치· 조언을 구하시오.
P337+P313 눈에 대한 자극이 지속되면 의학적인 조치· 조언를 구하시오.
NFPA 704
1
1 0

파미틴산 이소프로필 MSDS


Isopropyl palmitate

파미틴산 이소프로필 C화학적 특성, 용도, 생산

화학적 성질

Isopropyl palmitate is a clear, colorless to pale yellow-colored, practically odorless viscous liquid that solidifies at less than 16°C.

용도

isopropyl palmitate is an emollient and moisturizer, it also acts as a binder and solvent. Similar to isopropyl myristate, it is produced from the combination of palmitic acid (coconut or palm oil) and isopropyl alcohol. enzymes are able to metabolize this ingredient and studies do not show allergic reactions or toxicity. Some sources indicate comedogenicity potential.

정의

ChEBI: Isopropyl palmitate is a fatty acid ester obtained by the formal condensation of carboxy group of palmitic acid with propan-2-ol. Metabolite observed in cancer metabolism. It has a role as a human metabolite. It is a fatty acid ester and an isopropyl ester. It is functionally related to a hexadecanoic acid.

생산 방법

Isopropyl palmitate is prepared by the reaction of palmitic acid with propan-2-ol in the presence of an acid catalyst. A high-purity material is also commercially available, which is produced by enzymatic esterification at low temperatures.

일반 설명

Isopropyl palmitate is an analog of isopropyl myristate and an aliphatic ester used as a flavoring ingredient in food industry. It is one of the volatile compounds found in Psidium salutare fruits and boiled buckwheat flour.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Pharmaceutical Applications

Isopropyl palmitate is a nongreasy emollient with good spreading characteristics, used in topical pharmaceutical formulations and cosmetics such as: bath oils; creams; lotions; make-up; hair care products; deodorants; lip products; suntan preparations; and pressed powders.
Isopropyl palmitate is an established penetration enhancer for transdermal systems. It has also been used in controlled-release percutaneous films. Table I: Uses of isopropyl palmitate

부작용

Side effects for the skin: If overused, isopropyl palmitate may cause acne, blackheads, whiteheads, and clogged pores. Depending on the content of the ingredients in the product, the skin may experience some irritation. If isopropyl palmitate is used without dilution, it may cause comedoles. People with oily skin should also avoid isopropyl palmitate.
Side effects for hair: Excessive use of products containing isopropyl palmitate on hair can make hair look untidy, oily, and untidy due to excessive moisture in the hair. When there is an open wound on the scalp, isopropyl palmitate should also be avoided.

Safety

Isopropyl palmitate is widely used in cosmetics and topical pharmaceutical formulations, and is generally regarded as a relatively nontoxic and nonirritant material.
LD50 (mouse, IP): 0.1 g/kg

저장

Isopropyl palmitate is resistant to oxidation and hydrolysis, and does not become rancid. It should be stored in a well-closed container, above 16°C, and protected from light.

Regulatory Status

Included in the FDA Inactive Ingredients Database (topical and transdermal preparations). Used in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

파미틴산 이소프로필 준비 용품 및 원자재

원자재

준비 용품


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