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L-Epicatechin

L-Epicatechin 구조식 이미지
카스 번호:
490-46-0
상품명:
L-Epicatechin
동의어(영문):
Kakaol;(-)-EC;(+)-EC;Colatein;NSC 81161;EPICATECHIN;Acacatechin;epicatechol;Epicatechine;epi-catechol
CBNumber:
CB0454852
분자식:
C15H14O6
포뮬러 무게:
290.27
MOL 파일:
490-46-0.mol

L-Epicatechin 속성

녹는점
240 °C (dec.)(lit.)
알파
-55~-65゜(D/20℃)(c=1,CH3OH)
끓는 점
629.2 °C
밀도
1.593±0.06 g/cm3(Predicted)
저장 조건
-20°C
물리적 상태
neat
산도 계수 (pKa)
9.54±0.10(Predicted)
수용성
Soluble in water or alcohol
Merck
13,1912
BRN
92760
InChIKey
PFTAWBLQPZVEMU-UKRRQHHQSA-N
CAS 데이터베이스
490-46-0(CAS DataBase Reference)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 26-36
WGK 독일 3
RTECS 번호 KB3745000
F 고인화성물질 10-23
HS 번호 29329990
그림문자(GHS):
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P304+P340 흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P405 밀봉하여 저장하시오.

L-Epicatechin MSDS


L-Epicatechin

L-Epicatechin C화학적 특성, 용도, 생산

개요

(?)-Epicatechin is a polyketide synthase-derived polyphenol flavonoid that has been found in T. cacao and has diverse biological activities. It scavenges DPPH (Item No. 14805) radicals in a cell-free assay when used at a concentration of 5 μM. (?)-Epicatechin inhibits COX-1 (IC50 = 3.2 μM). It acts synergistically with epigallocatechin gallate (Item No. 70935) to induce apoptosis in, and reduce the proliferation of, PC-9 lung cancer cells when used at a concentration of 200 μM. (?)-Epicatechin (80 mg/kg) reduces LPS-induced increases in plasma creatinine and urea levels in a rat model of renal inflammation.

화학적 성질

white to light yellow crystal powde

용도

Potent antioxidant and antineoplastic agent.

용도

Catechin is a polyphenolic flavonoid that has been isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany. Catechin is a more potent antioxidant than ascorbate or α-tocopherol in certain in vitro lipid peroxidation assays. (?)-Epicatechin is a 2R,3R stereoisomer of catechin. Like catechin, (?)-epicatechin is a powerful antioxidant. It inhibits cyclooxygenase 1 (IC50 = 3.2 μM). Also, at 100 μM, (?)-epicatechin induces apoptosis in human adenocarcinoma PC-9 cells and stimulates the inhibition of tumor necrosis factor-α release from BALB-c/3T3 cells treated with epigallocatechin gallate.

용도

An antioxidant and natural product from green tea

정의

ChEBI: A catechin with (2R,3R)-configuration.

일반 설명

(?)-Epicatechin (EC) belongs to the group of flavanols and is abundantly present in cacao and cacao products. The chemical structure of EC includes an oxygenated heterocycle with a 4-hydroxyl group linked with two aromatic rings.

Biochem/physiol Actions

This antioxidant is found in chocolate. (-)-Epicatechin is linked with cardiovascular effects. It is considered as a dependable standard due to its availability in cacao seeds and cocoa products. The halogenating activity of myeloperoxidase can be restored by (-)-epicatechin.

L-Epicatechin 준비 용품 및 원자재

원자재

준비 용품


L-Epicatechin 공급 업체

글로벌( 387)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58
NanJing Spring & Autumn Biological Engineering CO., LTD.
0086 13815430202 0086 13815430202
sale02@cqherb.com CHINA 376 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 15421 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 9150 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29953 58
Chengdu Biopurify Phytochemicals Ltd.
18482058008 18080483897
maggie@biopurify.com China 2712 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
alice@crovellbio.com China 5942 58

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