InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem 속성
안전
InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem C화학적 특성, 용도, 생산
일반 설명
Potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM).Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. Activates c-Jun N-terminal kinase (JNK1) which initiates apoptosis. Inhibits NF-κBactivation (IC50 = 3 μM). This material is ≥95% pure by HPLC. A material with ≥98% purity by HPLC (Cat. No. 474791) and the solid form of this compound (Cat. No. 474787) are also available.
Biochem/physiol Actions
Cell permeable: yes
InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem 준비 용품 및 원자재
원자재
준비 용품
InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem 공급 업체
