β-Secretase Substrate IV, Fluorogenic - Calbiochem

β-Secretase Substrate IV, Fluorogenic - Calbiochem C화학적 특성, 용도, 생산

일반 설명

A highly sensitive fluorescence resonance energy transfer (FRET) peptide substrate (excitation max.: ~350 nm; emission max.: ~490), based on the GVNLDAEF sequence derived from the β-secretase site of the Swedish mutation of Amyloid Precursor Protein. Hydrolysis of the substrate at Leu-Asp bond by β-secretase results in fluorescence enhancement. Reported K_cat/k_m values (min^-1/μM) for pro-mempasin 2 and its proteolytically activated species Leu^28p-mempasin 2 are 0.044 and 0.040, respectively (at pH 4.5, 37°C).

Biochem/physiol Actions

Product does not compete with ATP.

β-Secretase Substrate IV, Fluorogenic - Calbiochem 준비 용품 및 원자재

원자재

준비 용품

β-Secretase Substrate IV, Fluorogenic - Calbiochem 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80