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RIMEXOLONE (100 MG)

RIMEXOLONE (100 MG) 구조식 이미지
카스 번호:
49697-38-3
상품명:
RIMEXOLONE (100 MG)
동의어(영문):
Org-6216;Rimexolone;(11β,16α,17β)-;RIMEXOLONE (100 MG);RIMEXOLONE fandachem;11β-Hydroxy-16α,17α-dimethyl-17β-propionylandrosta-1,4-dien-3-one;(17S)-11β-Hydroxy-16α,17α-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one;(11b,16a,17b)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one;(11β, 16α, 17β)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androstra-1,4-dien-3-one;Androsta-1,4-dien-3-one, 11-hydroxy-16,17-dimethyl-17-(1-oxopropyl)-, (11β,16α,17β)-
CBNumber:
CB0500540
분자식:
C24H34O3
포뮬러 무게:
370.52
MOL 파일:
49697-38-3.mol

RIMEXOLONE (100 MG) 속성

녹는점
258-268 ºC
알파
D +100° (c = 0.92 in pyridine)
끓는 점
507.0±50.0 °C(Predicted)
밀도
1.12
산도 계수 (pKa)
14.42±0.70(Predicted)
InChIKey
QTTRZHGPGKRAFB-OOKHYKNYSA-N
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
HS 번호 2937290000
그림문자(GHS):
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H360 태아 또는 생식능력에 손상을 일으킬 수 있음 생식독성 물질 구분 1A, 1B 위험
예방조치문구:
P201 사용 전 취급 설명서를 확보하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P308+P313 노출 또는 접촉이 우려되면 의학적인 조치· 조언를 구하시오.

RIMEXOLONE (100 MG) C화학적 특성, 용도, 생산

개요

Rimexolone, an ophthalmic corticosteroid, was launched in 1995 in the U.S.A. for the treatment of postoperative inflammation following ocular surgery and anterior uveitis. Rimexolone has high corticoid receptor affinity and is a potent local antiinflammatory agent with minimal systemic effects and virtually no atrophogenic action in many animal models studied, unique among a wide range of topical steroids. Rapid onset, long duration of action plus a superior safety profile are characteristics of rimexolone. It was also approved in Europe for the treatment of rheumatoid arthritis and is currently in clinical trials for tendinitis and osteoarthritis.

Originator

Akzo (Netherlands)

용도

Anti-inflammatory (local).

상표명

Vexol (Alcon).

일반 설명

Rimexolone, 11β-hydroxy-16α,17α-dimethyl-17-(1-oxopropyl)androsta-1,4-diene-3-one,like medrysone and fluorometholone, lacks the C21 OHgroup. In addition, rimexolone has an additional methylgroup in the 17 -position, a site where an OH group is typicallyfound. Rimexolone is available as a suspension forophthalmic use.

RIMEXOLONE (100 MG) 준비 용품 및 원자재

원자재

준비 용품


RIMEXOLONE (100 MG) 공급 업체

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