Astragaloside A

Astragaloside A 구조식 이미지
카스 번호:
83207-58-3
상품명:
Astragaloside A
동의어(영문):
Astragaloside IV;Astramembrannin i;Astragalin A;astragaloside A;Astragaloside A 5%;ASTRAGALOSIDE IV(P);Astragaloside IV(A);Astragaloside IV CRS;Astragaloside IV ,98%;Astragalus methylside
CBNumber:
CB0500944
분자식:
C41H68O14
포뮬러 무게:
784.97
MOL 파일:
83207-58-3.mol

Astragaloside A 속성

끓는 점
895.7±65.0 °C(Predicted)
밀도
1.39±0.1 g/cm3(Predicted)
저장 조건
under inert gas (nitrogen or Argon) at 2-8°C
용해도
DMF: 20 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
물리적 상태
결정성 고체
산도 계수 (pKa)
12.91±0.70(Predicted)
InChIKey
QMNWISYXSJWHRY-APZLXCBQNA-N
LogP
0.628 (est)
CAS 데이터베이스
83207-58-3

안전

HS 번호 29389090

Astragaloside A C화학적 특성, 용도, 생산

용도

Astragalosides are bioactive saponins isolated from dried roots of plants of the genus Astragalus, which is used in traditional Chinese medicine. Astragaloside A, also known as astragaloside IV, is known to have diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. More specifically, it protects cardiomyocytes from apoptosis resulting from ischemia/reperfusion and inhibits inflammation signaled through TNF-α. Furthermore, astragaloside A stimulates angiogenesis, promotes the differentiation of neural stem cells, and increases neuroregeneration.

정의

ChEBI: A pentacyclic triterpenoid that is cycloastragenol having beta-D-xylopyranosyl and beta-D-glucopyranosyl residues attached at positions O-3 and O-6 respectively. It is isolated from <ital Astragalus membranaceus var mongholicus.

benefits

Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases. It is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases. Astragaloside IV improves post-ischemic heart function and ameliorated reperfusion arrhythmias accompanied by a significant increase in myocardial antioxidative enzyme superoxide dismutase activity in rat hearts in vitro. While, Astragaloside IV's protective effect on heart function can be partially abrogated by the nitric oxide synthase inhibitor, Nomega-nitro-L-arginine methyl ester.

Pharmaceutical Applications

Astrageloside A has multiple pharmacologic effects, including anti-inflammatory, antifibrotic, antioxidative stress, anti-asthma, antidiabetes, immunoregulation, and cardioprotective effect via numerous signaling pathways. According to the existing studies and clinical practices, Astragaloside A possesses potential for broad application in many diseases.

Astragaloside A 준비 용품 및 원자재

원자재

준비 용품


Astragaloside A 공급 업체

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Chengdu King-tiger Pharm-chem. Tech. Co., Ltd.
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Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213
info@longyupharma.com China 2531 58

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