7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원

7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원
7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원 구조식 이미지
카스 번호:
35212-22-7
한글명:
7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원
동의어(한글):
7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원
상품명:
Ipriflavone
동의어(영문):
Ipriavone;Ipriflavon;7-ISOPROPOXYISOFLAVONE;Ipriflavone (Osteofix);tc80;osten;fl113;osteofix;YAMBOLAP;Iprosten
CBNumber:
CB0698496
분자식:
C18H16O3
포뮬러 무게:
280.32
MOL 파일:
35212-22-7.mol
MSDS 파일:
SDS

7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원 속성

녹는점
116-120 °C(lit.)
끓는 점
363.04°C (rough estimate)
밀도
1.2170 (rough estimate)
굴절률
1.4700 (estimate)
저장 조건
Sealed in dry,Room Temperature
용해도
DMF:20.0(Max Conc. mg/mL);71.35(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.71(Max Conc. mM)
DMSO:33.11(Max Conc. mg/mL);118.11(Max Conc. mM)
Ethanol:1.5(Max Conc. mg/mL);5.35(Max Conc. mM)
물리적 상태
powder to crystal
색상
흰색에서 거의 흰색
Merck
14,5074
InChI
InChI=1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3
InChIKey
SFBODOKJTYAUCM-UHFFFAOYSA-N
SMILES
C1OC2=CC(OC(C)C)=CC=C2C(=O)C=1C1=CC=CC=C1
LogP
4.245 (est)
CAS 데이터베이스
35212-22-7(CAS DataBase Reference)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 24/25-36/37/39-27-26
WGK 독일 2
RTECS 번호 DJ3100500
HS 번호 29329990
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원 MSDS


Ipriflavone

7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원 C화학적 특성, 용도, 생산

개요

Ipriflavone, a derivative of isoflavone, is a calcium metabolism regulator useful in the treatment of primary and secondary osteoporosis, as well as disorders of osteogenesis. It appears to be without significant side-effects.

화학적 성질

white powder

용도

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone) has been used as a model drug in a study to functionalize the mesoporous bioactive glasses (MBG). Study suggested that since ipriflavone is a hydrophobic anti-osteoporotic drug, it easily attaches to the surface of MBG and results in long-term drug delivery.

정의

ChEBI: Ipriflavone is a member of the class of isoflavones that is isoflavone in which the hydrogen at position 7 is replaced by an isopropoxy group. A synthetic isoflavone, it was formerly used for the treatment of osteoporosis, although a randomised controlled study failed to show any benefit. It is still used to prevent osteoporosis in post-menopausal women. It has a role as a bone density conservation agent. It is a member of isoflavones and an aromatic ether.

benefits

Ipriflavone is used clinically to treat osteoporosis. Bodybuilders also use ipriflavone, but enough experimental data supports this purpose. It has been shown to have anti-inflammatory and antioxidant activity. It helps to reduce bone loss, increase bone density, and reduce the risk of developing osteoporosis. It has also been found to help reduce neuroinflammation . In addition, it has been found to help reduce the risk of certain types of cancer, improve cognitive function and reduce the risk of depression.

일반 설명

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone), a synthetic flavonoid, is reported to stimulate the activity of osteoblasts. It is reported to promote the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like (ROB) cells as well as the activity of alkaline phosphatase. Ipriflavone, an isoflavone derivative, is a new drug used to decrease bone loss in osteoporosis.

부작용

Ipriflavone should be taken under medical supervision only. It can produce side effects such as stomach pain, diarrhoea, dizziness, etc. It may have a sudden increase in the WBC count if administered for six months or more. When the treatment with Ipriflavone is on, it is suggested that the WBC count should be monitored. 

7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원 준비 용품 및 원자재

원자재

준비 용품


7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원 공급 업체

글로벌( 371)공급 업체
공급자 전화 이메일 국가 제품 수 이점
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD
+86-576-88902229;+86-0576-88902229 +8613968687450
yuxin@yuxchem.com China 122 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 992 58
Hebei Jingbo New Material Technology Co., Ltd
+8619931165850
hbjbtech@163.com China 1000 58
Hebei Saisier Technology Co., LTD
+86-18400010335 +86-13102810335
admin@hbsaisier.cn China 747 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806
sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714
fandachem@gmail.com China 9348 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
Jinan Jianfeng Chemical Co., Ltd
0531-88110457; +8615562555968
info@pharmachemm.com China 222 58

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