아이소-바닐린
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아이소-바닐린 속성
- 녹는점
- 113-116 °C
- 끓는 점
- 179 °C15 mm Hg(lit.)
- 밀도
- 1.20
- 증기압
- 0Pa at 20℃
- 굴절률
- 1.4945 (estimate)
- 인화점
- 179°C/15mm
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 아세톤과 메탄올에 용해됩니다.
- 산도 계수 (pKa)
- pK1:8.889 (25°C)
- 물리적 상태
- 수정 같은
- 색상
- 희미한 갈색
- 수용성
- 2.27g/L at 20℃
- 감도
- Air Sensitive
- BRN
- 1073021
- InChIKey
- JVTZFYYHCGSXJV-UHFFFAOYSA-N
- LogP
- 0.95 at 20℃
- CAS 데이터베이스
- 621-59-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36/37-36 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | CU6540000 | ||
| 위험 참고 사항 | Irritant | ||
| TSCA | Yes | ||
| HS 번호 | 29124900 |
아이소-바닐린 C화학적 특성, 용도, 생산
화학적 성질
Light Tan Cyrstalline Solid용도
3-Hydroxy-4-methoxybenzaldehyde was used as starting reagent during the two-step stereoselective synthesis of the anticancer drug (Z)-combretastatin A-4 and glycitein synthesis.주요 응용
Isovanillin is a kind of fragrance and isomer of vanillin. it has unique properties than vanillin, its fragrance can change with the change of ambient temperature, so it is especially suitable for special cosmetics and some special fragrance industries. Isovanillin is a selective inhibitor of aldehyde oxidase. It is not a substrate of that enzyme, and is metabolized by aldehyde dehydrogenase into isovanillic acid, which could make it a candidate drug for use in alcohol aversion therapy.제조 방법
Synthesis of isovanillin: 4-Hydroxybenzaldehyde is used as raw material, firstly react with bromine to obtain 3-bromo-4-hydroxybenzaldehyde, then react with methyl iodide to obtain 3-bromo-4-methoxybenzaldehyde, and then hydrolyzed under the action of sodium hydroxide and cuprous chloride to produce isovanillin. The yield was 64.1%.일반 설명
3-Hydroxy-4-methoxybenzaldehyde on condensation with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide yields Schiff-bases. It undergoes condensation reaction with1-azabicyclo[2.2.2]octan-3-one to give (Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one.Purification Methods
Crystallise isovaniline from H2O or *C6H6. The oxime has m 147o. [Beilstein 8 IV 1764.]아이소-바닐린 준비 용품 및 원자재
원자재
준비 용품
테트라하이드로다이페룰로일메탄
2-Chloroveratraldehyde
6-HYDROXY-7-METHOXYCOUMARIN
3-CYCLOPENTYLOXY-4-METHOXYBENZALDEHYDE
3-HYDROXY-4-METHOXYPHENETHYLAMINE HYDROCHLORIDE
페놀도팜
COMBRETASTATIN A-4
5-BROMOPROTOCATECHUALDEHYDE
(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine
3-(3-morpholinylpropoxy)-4-methoxybenzonitrile
2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE
S- (+)-Rolipram
4-METHOXY-3-HYDROXYACETOPHENONE
oxidopamine
2-METHOXY-5-METHYLPHENOL
4-Methoxy-3-(phenethyloxy)benzaldehyde
3-(3-Hydroxy-4-methoxyphenyl)-2-propenoic acid methyl ester
아이소-바닐린 공급 업체
글로벌( 700)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7786 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 401 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 |
sales@nbinno.com | CHINA | 925 | 58 |