프로토폴린 IX
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프로토폴린 IX 속성
- 녹는점
- >300 °C(Solv: acetone (67-64-1))
- 끓는 점
- 629.06°C (rough estimate)
- 밀도
- 1.1829 (rough estimate)
- 굴절률
- 1.6000 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- DMSO (약간 용해됨)
- 물리적 상태
- 가루
- 색상
- 보라
- 수용성
- 106.9mg/L(25℃)
- 감도
- light sensitive
- Merck
- 13,7990
- BRN
- 380795
- 안정성
- 감광성
- InChIKey
- FEDYMSUPMFCVOD-UJJXFSCMSA-N
- CAS 데이터베이스
- 553-12-8
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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유해·위험 문구: |
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예방조치문구: |
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프로토폴린 IX C화학적 특성, 용도, 생산
용도
Protoporphyrin IX has been used:- as a standard in protoporphyrin assays
- in fluorescence spectra analysis
- to treat cells in cell culture to study heme-mediated ferroportin 1 transcription
정의
ChEBI: A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyri s.일반 설명
Protoporphyrin IX belongs to the porphyrin family, which are a class of tetrapyrroles. It is the iron-free form of hemin and amphiphilic in nature. It is the precursor of heme in its biosynthetic pathway.효소 저해제
This iiron-free, immediate precusor of heme (FWfree-acid = 562.67 g/mol; CAS 553-12-8; brownish-yellow solid; soluble in a number of organic solvents; disodium and dipotassium salts solublized in the presence of Tween 80) has lmax values in 25% HCl are 602.4, 582.2, and 557.2 nm. Protoporphryrin IX is also an activator of guanylate cyclase. See also Iron Protoporphyrin IX; Heme; Hemin Target(s): aminolevulinate aminotransferase; 5-aminolevulinate synthase; glutamate: glyoxylate aminotransferase; glutathione S-transferase; glyoxalase I, or lactoylglutathione lyase; guanylate cyclase; heme oxygenase; hydroxymethylbilane synthase, or porphobilinogen deaminase; nitric-oxide synthase; porphobilinogen synthase, or 5-aminolevulinate dehydratase; succinyl-CoA synthetase; tryptophan pyrrolase, or tryptophan 2,3-dioxygenase; and uroporphyrinogen decarboxylase.Purification Methods
Protoporphyrin IX (3,18-divinyl-2,7,13,17-tetramethylporphin-8,12-dipropionic acid, ooporphyrin) [553-12-8] M 562.7, pKEst ~ 4.8. Protoporphyrin IX is purified by dissolving (4g) in 98-100% HCOOH (85mL), diluting with dry Et2O (700mL) and keeping at 0o overnight. The precipitate is collected and washed with Et2O, then H2O, and dried in a vacuum at 50o over P2O5. It crystallises from aqueous pyridine and from Et2O in monoclinic, brownish-yellow prisms. The UV max values in 25% HCl are 557.2, 582.2 and 602.4nm. It is freely soluble in ethanolic HCl, AcOH, CHCl3, and Et2O containing AcOH. It forms sparingly soluble diNa and diK salts. [Ramsey Biochemical Preparations 3 39 1953, UV: Holden Aust J. Exptl Biol and Med Sci 15 412 1937, Garnick J Biol Chem 175 333 1948, IR: Falk & Willis Aust J Sci Res [A] 4 579 1951, Beilstein 26 IV 3042.]프로토폴린 IX 준비 용품 및 원자재
원자재
준비 용품
프로토폴린 IX 공급 업체
글로벌( 220)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5873 | 58 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 7621 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29822 | 58 |
Chengdu Aslee Biopharmaceuticals, Inc. | 28-85305008 |
CHINA | 964 | 58 | |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34571 | 58 |
프로토폴린 IX 관련 검색:
2,2-비스(히드록시메틸)프로판 산 클로로디메틸비닐실란 아세트산 엽산 시트르산 비닐 프로피온산염 니켈 테트라페닐포르핀 프로토폴린 IX
dimethyl protoporphyrin IX,Protoporphyrin IX dimethyl ester,PROTOPORPHYRIN IX DIMETHYL ESTER FROM*OX HEMIN
PROTOPORPHYRINATO ZINC
Hyaluronic acid
4-(4-CHLORO-BENZYLOXY)-PHENYLAMINE
SODIUM ORTHOSILICATE
PROTAMINE SULFATE
Protopine
Protocatechuic acid
Ascoric Acid
1,1,1-Trimethoxypentane