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ACRIDINE ORANGE

ACRIDINE ORANGE 구조식 이미지

카스 번호:: 65-61-2

상품명:: ACRIDINE ORANGE

동의어(영문):: AO;AOX1;Lysotraker;CI NO 46005;BASIC ORANGE;-Cellstain-Ao;Euchrysine 3r;EUCHRYSINE 3RX;acridineoranger;RHODULINE ORANGE

CBNumber:: CB0747468

분자식:: C17H20ClN3

포뮬러 무게:: 301.82

MOL 파일:: 65-61-2.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 130

ACRIDINE ORANGE 속성

녹는점: 284-287 °C(lit.)

밀도: 1.001 g/mL at 20 °C

굴절률: n20/D 1.338

저장 조건: -20°C

용해도: 물, 에탄올, 디메틸설폭사이드에 용해됨

물리적 상태: 가루

산도 계수 (pKa): -3.2, 10.5(at 25℃)

색상 색인 번호: 46005

색상: 주황색에서 빨간색으로

최대 파장(λmax): 500 nm

BRN: 3734978

생물학 분야의 응용: Detecting cancer cells,spores,human papilloma virus (HPV),stress biomarkers; treating amyloid associated diseases,lupus,pathogen infections; apoptosis assays; cytotoxicity assays

주요 응용: Adhesives; aluminophosphate crystalline materials; detecting clay particles; display device; evaluating fiber surface characteristics; glass matrixes; imaging material; inks; lasers; recording materials; photoresists; textiles; thin films; tracers for hydrology; wiring boards

CAS 데이터베이스: 65-61-2

EPA: C.I. Basic Orange 14 (65-61-2)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

안전지침서	22-24/25
WGK 독일	3
RTECS 번호	AR7601000
HS 번호	32041300
독성	dnd-mus:ast 20 mmol/L BBACAQ 374,96,74

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H341	유전적인 결함을 일으킬 것으로 의심됨 (노출되어도 생식세포 유전독성을 일으키지 않는다는 결정적인 증거가 있는 노출경로가 있다면 노출경로 기재)	생식세포 변이원성 물질	구분 2	경고		P201,P202, P281, P308+P313, P405,P501

예방조치문구:

P201	사용 전 취급 설명서를 확보하시오.
P202	모든 안전 조치 문구를 읽고 이해하기 전에는 취급하지 마시오.
P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P308+P313	노출 또는 접촉이 우려되면 의학적인 조치· 조언를 구하시오.
P405	밀봉하여 저장하시오.
P501	...에 내용물 / 용기를 폐기 하시오.

ACRIDINE ORANGE C화학적 특성, 용도, 생산

화학적 성질

dark orange to brown powder

용도

Acridine orange is a dye that interacts with DNA and RNA by intercelation or electrostatic attraction. This cationic dye has been used as a fluorescent stain for nucleic acids in agarose and polyacrylamide gels.

제조 방법

4,4 ‘-Bis (N, N-dimethyl) aminodiphenylmethane obtained dinitration of 4,4′ – bis (N, N-dimethyl) amino-2 ‘- dinitro-diphenyl methane reduction, and with an acid of heat, so that the diamino compound is cyclized product is oxidized and then cyclized and converted into zinc chloride double salt.

Safety Profile

Mutation data reported. Whenheated to decomposition it emits very toxic fumes of HCl,Cl??, and NOx.

효소 저해제

This cell-permeable dye (FWfree-base = 265.36 g/mol; CAS 65-61-2), also known as N,N,N',N'-tetramethylacridine-3,6-diamine, is an intercalator that binds tightly to nucleic acids. Binding to DNA is characterized by excitation maximum at 502 nm (cyan) and an emission maximum at 525 nm, producing a green fluorescence. (A 120 μM solution of acridine orange will detect 25-50 ng DNA per band in an agarose or polyacrylamide gel.) Binding to RNA is characterized by an excitation maximum at 460 nm and the emission maximum is located at 650 nm, yielding a reddish-orange fluorescence. Acridine orange also penetrates acidic compartments (e.g., lysosomes and phagolysosomes); upon protonation, the dye emits orange light when excited by blue light.

ACRIDINE ORANGE 준비 용품 및 원자재

원자재

준비 용품

Acridinium, 3,6-bis(dimethylamino)-10-methyl-, methyl sulfate

ACRIDINE ORANGE 공급 업체

글로벌( 130)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7845	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12468	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
GERBU Biotechnik GmbH	+49-62217264160 +49-62217264160	found@gerbu.de	Germany	4	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
ZHEJIANG JIUZHOU CHEM CO., LTD	+86-0576225566889 +86-13454675544	admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com	China	20000	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49999	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58

ACRIDINE ORANGE 관련 검색:

아크리딘 3,6-디아미노아크리딘 헤미황산염 ACRIFLAVINE 7-Aminoquinoline Basic Orange 14 ACRIDINE ORANGE (C.I. 46005:1),ACRIDINE ORANGE BASIC,ACRIDINE ORANGE BASE ACRIDINE HYDROCHLORIDE ACRIDINE ORANGE 3,6-DIAMINOACRIDINE HYDROCHLORIDE ACRIDINE ORANGE 10-NONYL BROMIDE,NONYL ACRIDINE ORANGE ACRIDINE ORANGE-10-OCTADECYL BROMIDE,3,6-Bis(dimethylamino)-10-octadecylacridinium bromide, Acridine orange-10-octadecyl bromide ACRIDINE ORANGE-10-DODECYL BROMIDE,3,6-Bis(dimethylamino)-10-dodecylacridinium bromide, Acridine orange-10-dodecyl bromide ACRIDINE ORANGE, 1/2ZNCL Acridine Orange in Acetate Buffer ACRIDINE ORANGE 10-NONYL BROMIDE (NONYL ACRIDINE ORANGE) DIMETHYL-QUINOLIN-7-YL-AMINE Acridine Orange + DNA Acridine Orange + RNA