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6',7'-DIHYDROXYBERGAMOTTIN

6',7'-DIHYDROXYBERGAMOTTIN 구조식 이미지

카스 번호:: 145414-76-2

상품명:: 6',7'-DIHYDROXYBERGAMOTTIN

동의어(영문):: 6',7'-DIHYDROXYBERGAMOTTIN;6,7-dihydroxybergaMottin(DHB);4-[[(2E)-6,7-Dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one;7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-

CBNumber:: CB0765541

분자식:: C21H24O6

포뮬러 무게:: 372.41

MOL 파일:: 145414-76-2.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 48

6',7'-DIHYDROXYBERGAMOTTIN 속성

녹는점: 112-113 °C

끓는 점: 578.2±50.0 °C(Predicted)

밀도: 1.260

저장 조건: 2-8°C

용해도: 에탄올: 가용성

산도 계수 (pKa): 14.65±0.29(Predicted)

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 흰색에서 황백색까지

안전

WGK 독일	3

6',7'-DIHYDROXYBERGAMOTTIN C화학적 특성, 용도, 생산

개요

6,7-dihydroxy Bergamottin (6,7-DHB) is a potent inhibitor of CYP3A4 (IC₅₀ = 25 μM). It appears to be the primary compound in grapefruit juice that is responsible for inhibition of testosterone 6β-hydrolase activity. Ingestion of grapefruit juice during treatment regimes with drugs normally metabolized by cytochrome P450 enzymes of the CYP3A subfamily results in a substantial increase in plasma concentration of these agents. However, giving a patient grapefruit juice or just 6,7-DHB could be advantageous in cases where a drug is metabolized too quickly by CYP3A4.

용도

A minor metabolite of Bergamottin. Metabolization of Bergamottin by cytochromes P 450 2B6 and 3A5.

Biochem/physiol Actions

CYP3A4 inhibitor.

6',7'-DIHYDROXYBERGAMOTTIN 준비 용품 및 원자재

원자재

준비 용품

6',7'-DIHYDROXYBERGAMOTTIN 공급 업체

글로벌( 48)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Wuhan Nutra Biotechnology Co.,Ltd	+8617786394783	nutrabiotech@outlook.com	China	300	58
Wuhan Kemi-Works Chemical Co., Ltd.	+86-2785736489 +8618171418573	sales@kemiworks.com	China	704	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
China DongFan Chemical Co.,LTD	86-0571-85151182		China	5700	66
Wuhan Kemi-Works Chemical Co., Ltd	027-85736489	info@kemiworks.net	China	542	57
Wuhan HengHeDa Pharm Co., Ltd.	27-27-84888682 18086046872	hhdpharm@hotmail.com	China	117	55
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

6',7'-DIHYDROXYBERGAMOTTIN 관련 검색:

4-ALLYLOXYCOUMARIN 6',7'-DIHYDROXYBERGAMOTTIN 4-ETHOXYCOUMARIN 1-BENZOFURAN-5-YLMETHANOL