Bendamustine hydrochloride
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Bendamustine hydrochloride 속성
- 녹는점
- 149-151°C
- 저장 조건
- room temp
- 용해도
- H2O: >30mg/mL
- 물리적 상태
- 가루
- 색상
- 회백색
- Merck
- 14,1034
- InChIKey
- ZHSKUOZOLHMKEA-UHFFFAOYSA-N
- CAS 데이터베이스
- 3543-75-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 60-61-22-40 | ||
| 안전지침서 | 36-37 | ||
| 유엔번호(UN No.) | UN 2811 6.1 / PGIII | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | DE1590000 | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | III | ||
| HS 번호 | 29339900 | ||
| 독성 | LD50 (monohydrate) in mice, rats (mg/kg): 400-500, 200-300 orally; 80, 40 i.v. (Horn) |
Bendamustine hydrochloride C화학적 특성, 용도, 생산
화학적 성질
Pale Brown Crystals용도
Bendamustine hydrochloride hydrate has been used as:- a chemotherapy agent for chronic lymphocytic leukemia (CLL) samples to monitor spliced and unspliced gene expression
- an inhibitor to E3 ubiquitin-protein ligase RNF3 (HOIP) in?matrix-assisted laser desorption ionization time-of-flight mass spectrometry?(MALDI-TOF) assay
- a cytotoxic chemotherapeutic drug in high-throughput screening to test interaction with BAY87-2243
일반 설명
Bendamustine comprises 2-chloroethylamine alkylating group, a butyric acid side chain and a benzimidazole ring in its structure and is a nitrogen mustard. It is catabolized in the liver by the enzyme cytochrome P450 1A2 into γ hydroxyl-bendamustine and N-desmethyl-bendamustine.생물학적 활성
Cytostatic agent that displays activity in non-Hodgkin's lymphomas. Exhibits bifunctionality; combines DNA alkylating properties with those of purine analogs.Bendamustine hydrochloride 준비 용품 및 원자재
원자재
Pentanoic acid, 5-[(2,4-dinitrophenyl)methylamino]-5-oxo-, methyl ester
Pentanoic acid, 5-[(2,4-dinitrophenyl)amino]-5-oxo-, methyl ester
isopropyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate
5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester
1H-Benzimidazole-2-butanoic acid, 5-[bis(2-hydroxyethyl)amino]-1-methyl-, 1-methylethyl ester
1-클로로-2.4-디니트로벤젠
5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
Methyl 4-(chloroformyl)butyrate
BendaMustine IMpurity C
2,4-디니트로아닐린
5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid methyl ester
N-methyl-2,4-dinitroaniline
N1-Methyl-4-nitro-o-phenyldiamin
준비 용품
Bendamustine hydrochloride 공급 업체
글로벌( 398)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12457 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| Lianyungang happen teng technology co., LTD | 15950718863 |
wang666xt@163.com | CHINA | 295 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
| Beijing Yibai Biotechnology Co., Ltd | 0086-182-6772-3597 |
sales04@yibaibiotech.com | CHINA | 419 | 58 |
Bendamustine hydrochloride 관련 검색:
메클레타민 수화염화물
AMbroxoliMpurity
BroMo Prasugrel IMpurity
5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester
5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid
5-[bis-(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
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