Deserpidine

Deserpidine 구조식 이미지
카스 번호:
131-01-1
상품명:
Deserpidine
동의어(영문):
Harmonyl;Raunormine;Canescine;Reserpidine;Recanescine;DESERPIDINE;Reserpine Impurity 3;Deserpidine USP/EP/BP;Deserpidine Solution, 100ppm;methyl 17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate
CBNumber:
CB0834483
분자식:
C32H38N2O8
포뮬러 무게:
578.65
MOL 파일:
131-01-1.mol

Deserpidine 속성

녹는점
228-232°; mp 230-232°; mp 138° and 226-232° with resolidification at 175°
알파
D20 -163° (c = 0.5 in pyridine)
끓는 점
638.28°C (rough estimate)
밀도
1.2277 (rough estimate)
굴절률
1.6260 (estimate)
저장 조건
-20°C Freezer
용해도
클로로포름(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
6.68 in 40% methanol
색상
흰색에서 황백색까지
CAS 데이터베이스
131-01-1(CAS DataBase Reference)
NIST
Deserpidine(131-01-1)

안전

Deserpidine C화학적 특성, 용도, 생산

화학적 성질

Crystalline solid; exists in three crystallineforms; mp 228–232°C (442.4–449.6°F); soluble in chloroform and methanol, insolublein water; pK 6.68 in saturated solution of40% methanol in water.

용도

Deserpidine is found and extracted fromthe roots of Rauwolfia canescens L., andApocyanaceae. Therapeutically, it is used asan antihypertensive agent.

건강위험

The pharmacological properties of deserpi dine are similar to those of reserpine, causingsedation and tranquilization. Toxic effectsfrom high doses include drowsiness, depres sion, nausea, diarrhea, abdominal cramps,and hypotension. It is less toxic than reserpine. However, the poisoning effects may begreater than those of other Rauwolfia alka loids, such as rescinnamine. An oral LD50value in mice is 500 mg/kg.There is some evidence of its carcinogenic actions in animals and humans. Ratsgiven oral doses of 54 mg/kg over 77 weeksdeveloped blood tumor. In humans, it mayproduce tumors in skin and appendages.Cancer-causing properties of deserpidine,however, are not yet fully established.

Deserpidine 준비 용품 및 원자재

원자재

준비 용품


Deserpidine 공급 업체

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