2-Chloro-5-hydroxypyrimidine
|
|
2-Chloro-5-hydroxypyrimidine 속성
- 녹는점
- 195-196 °C
- 끓는 점
- 328.1±15.0 °C(Predicted)
- 밀도
- 1.513±0.06 g/cm3(Predicted)
- 저장 조건
- under inert gas (nitrogen or Argon) at 2-8°C
- 산도 계수 (pKa)
- 6.17±0.23(Predicted)
- CAS 데이터베이스
- 4983-28-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
HS 번호 | 29335990 |
---|
그림문자(GHS): | |||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
신호 어: | Warning | ||||||||||||||||||||||||||||
유해·위험 문구: |
|
||||||||||||||||||||||||||||
예방조치문구: |
|
2-Chloro-5-hydroxypyrimidine C화학적 특성, 용도, 생산
용도
2-Chloro-5-hydroxypyrimidine is an intermediate used to synthesize tandospirone derivatives with anxiolytic activities.Synthesis
2-Chloro-5-methoxypyrimidine (0.46 g, 3.18 mmol) in methylene chloride (10 mL) was treated with 1.0 N boron tribromide (16 mL, 16 mmol) at room temperature. The solution was stirred overnight. After that, the reaction was partitioned between saturated NaHCO3 and DCM. The aqueous layer was extracted with additional DCM. Combined the organic layers and dried (MgSO4), filtered, and concentrated to obtain the crude product. The residue was purified by flash column chromatography on silica gel to give 2-Chloro-5-hydroxypyrimidine.2-Chloro-5-hydroxypyrimidine 준비 용품 및 원자재
원자재
준비 용품
2-Chloro-5-hydroxypyrimidine 공급 업체
글로벌( 263)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 |
shangli@bocchem.com | China | 138 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 885 | 50 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 6992 | 58 |
2-Chloro-5-hydroxypyrimidine 관련 검색:
글리콜산 2-이소프로필-6-메틸-4-피리미디놀 술파디아진 우라실 크리신 실버(I) 설파다이아진 4-히드록시벤즈알데히드 클로로디플루오르메탄
HYDROXYAPATITE TYPE I
2-Chloropyrimidine
Hydroxy silicone oil
5-Hydroxypyrimidine
2-Chloro-5-fluoropyrimidine
Tandospirone
1-N-Boc-4-pyriMidin-2-yl-piperazine
(3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione
Camptothecin Series--10-hydroxycamptothecin
2,4-Dichloro-5-methoxypyrimidine