SULCONAZOLE

SULCONAZOLE 구조식 이미지
카스 번호:
61318-90-9
상품명:
SULCONAZOLE
동의어(영문):
Sulconazol;SULCONAZOLE;SULCONAZOLE USP/EP/BP;Sulconazle Impurity 3;1-(2-((4-Chlorobenzyl);-2-(2,4-dichlorophenyl);Uniconazole sulfur nitrate;Quizalofop Impurity 8(Propaquizafop);Sulconazole (base and/or unspecified salts);1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-iMidazole
CBNumber:
CB1102530
분자식:
C18H15Cl3N2S
포뮬러 무게:
397.75
MOL 파일:
61318-90-9.mol

SULCONAZOLE 속성

끓는 점
558.2±50.0 °C(Predicted)
밀도
1.34±0.1 g/cm3(Predicted)
저장 조건
2-8°C
산도 계수 (pKa)
6.55±0.12(Predicted)
CAS 데이터베이스
61318-90-9

안전

SULCONAZOLE C화학적 특성, 용도, 생산

용도

Sulconazole (Exelderm) is a synthetic, sulfur-substituted imidazole that is structurally related to the other imidazole antifungals (ketoconazole, econazole, and miconazole). It is postulated to inhibit 14-α-demethylase for decreased ergosterol synthesis, increased cell membrane permeability, and resultant cell death. It is active against most dermatophytes, yeast, and P. orbiculare. It also displays activity against some aerobic and anaerobic gram-positive bacteria. Sulconazole is a mild inducer of the cytochrome P-450 microsomal enzymes CYP1A1 and CYP2B1 and could theoretically induce the metabolism of other drugs.

정의

ChEBI: A member of the class of imidazoles that is 1-ethyl-1H-imidazole in which one of the hydrogens of the methyl group is replaced by a (4-chlorobenzyl)sulfanediyl group while a second is replaced by a 2,4-dichlorophenyl group.

Indications

Sulconazole (Exelderm) is a synthetic, sulfur-substituted imidazole that is structurally related to the other imidazole antifungals (ketoconazole, econazole, and miconazole). It is postulated to inhibit 14-α-demethylase for decreased ergosterol synthesis, increased cell membrane permeability, and resultant cell death. It is active against most dermatophytes, yeast, and P. orbiculare. It also displays activity against some aerobic and anaerobic gram-positive bacteria. Sulconazole is a mild inducer of the cytochrome P-450 microsomal enzymes CYP1A1 and CYP2B1 and could theoretically induce the metabolism of other drugs.

Solubility in organics

1 part in 3,333 (water), 1 part in 100 (ethanol), 1 part in 130 (acetone), 1 part in 333 (chloroform), 1 part in 2000 (dioxan), 1 part in 71 (methanol), 1 part in 286(chloromethane), 1 part in 10 (pyridine), 1 part in 2000 (toluene).

SULCONAZOLE 준비 용품 및 원자재

원자재

준비 용품


SULCONAZOLE 공급 업체

글로벌( 51)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Zhejiang ZETian Fine Chemicals Co. LTD
18957127338
stella@zetchem.com China 2141 58
Shaanxi Dideu Medichem Co. Ltd
18192627656
1012@dideu.com China 3422 58
Career Henan Chemica Co
+86-0371-86658258 15093356674;
laboratory@coreychem.com China 30255 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
sales@tnjchem.com China 34572 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 29271 58
AFINE CHEMICALS LIMITED
0571-85134551
info@afinechem.com CHINA 15377 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739
info@dycnchem.com CHINA 52867 58
Hebei Duling International Trade Co. LTD
+8618032673083
sales05@hbduling.cn China 15745 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49739 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490
info@gihichemicals.com China 49999 58

Copyright 2019 © ChemicalBook. All rights reserved