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포비돈요오드

포비돈요오드
포비돈요오드 구조식 이미지
카스 번호:
25655-41-8
한글명:
포비돈요오드
동의어(한글):
POVI디NE-요오드;포비돈요오드;포비딘-요오드;포비딘-요오드(POVIDINE-IODINE)
상품명:
Povidone iodine
동의어(영문):
I-PVP;pvp-1;PVP-I;videne;disphex;inadine;isodine;braunol;efo-dine;betadine
CBNumber:
CB1121625
분자식:
C8H15NO
포뮬러 무게:
141.2108
MOL 파일:
25655-41-8.mol

포비돈요오드 속성

녹는점
300 °C
저장 조건
Keep in dark place,Inert atmosphere,Room temperature
용해도
H2O: soluble100mg/mL
물리적 상태
Powder
색상
Yellow-brown
수용성
Soluble in water, ethyl alcohol, isopropyl alcohol, polyethylene glycol and glycerol. Insoluble in chloroform, carbon tetrachloride, hexane, acetone and petroleum ether.
Merck
13,7784
InChIKey
FAAHNQAYWKTLFD-UHFFFAOYSA-N
CAS 데이터베이스
25655-41-8(CAS DataBase Reference)
EPA
Povidone-iodine (25655-41-8)

안전

안전지침서 24/25-22
WGK 독일 2
RTECS 번호 TR1579600
TSCA Yes
HS 번호 29339900
유해 물질 데이터 25655-41-8(Hazardous Substances Data)
기존화학 물질 KE-13325

포비돈요오드 MSDS


Betadine

포비돈요오드 C화학적 특성, 용도, 생산

개요

Povidone-iodine is an iodophor. A 10% povidoneiodine solution contains 1% available iodine, but free iodine is at a concentration of 0.001%. Occupational exposure can cause irritant rather than allergie contact dermatitis in healtheare workers.

화학적 성질

yellowish to reddish-brown powder

Originator

Betadine ,Purdue Frederick ,US ,1957

용도

Topical anti-infective

용도

PVP-I is a broad spectrum antiseptic for topical application. It is used in first aid for minor cuts, grazes, burns, abrasions and blisters. PVP-I has broad applications in medicine as a surgical scrub; for pre- and post-operative skin cleansing; for the

Manufacturing Process

12 g of dry polyvinylpyrrolidone having a K value of 90 (water content about 2 to 3%) was added to 6 g of solid iodine crystals in a glass bottle containing a few pebbles and beads. This was rolled for 3 days on a roller mill with occasional manual stirring to loosen the material caked on the sides of the bottle. Analysis showed that the thus-obtained product contained 35.4% total iodine and 31.91% available iodine. The material was heat-treated at 95°C for 64 hours in a closed glass bottle with occasional stirring. On completion of this treatment, analysis showed that the material contained 35.3% total iodine, 25.7% available iodine, according to US Patent 2,706,701.

상표명

Betadine (Alcon); E-Z Prep (Becton Dickinson Microbiology).

Therapeutic Function

Topical antiinfective

색상 색인 번호

Povidone-iodine is iodophor, used as a topical antiseptic. A 10% povidone-iodine solution contains 1% available iodine, but free-iodine is at 0.1% concentration. Skin exposure causes irritant rather than allergic contact dermatitis. In such a situation, however, iodine seems to be the true hapten.

색상 색인 번호

Prilocaine in a local anesthetic of the amide group. It can induce allergic contact dermatitis, particularly from EMLA? cream.

Veterinary Drugs and Treatments

An iodophore antiseptic, povidone iodine is rapidly bactericidal (against gram-positive and – negative bacteria) at low concentration. Also fungicidal and sporicidal (as a 1% aqueous solution). It is commonly used as a topical pre-surgical skin cleaner/antiseptic, but is infrequently used in small animal dermatology due to its drying, irritating and staining effects.
Povidone acts by slowly releasing iodine to tissues. Indicated for superficial pyoderma and Malassezia dermatitis.

Veterinary Drugs and Treatments

Dilute solutions of povidone iodine (1% – 5%) have been utilized for chemical debridement of loose epithelium in canine indolent ulcers. 5% povidone iodine has also been used as an antifungal for fungal keratitis, but must be lavaged from the eye within 5 minutes to prevent damage to corneal epithelium. Generally, povidone iodine is only used once daily and then rinsed off when used in the eye as an anti-fungal. There has also been a renewed interest in utilizing povidone iodine in treating feline herpes keratitis. Solutions of commercially available 10% povidone iodine are diluted in physiologic saline to concentrations of 0.5 – 1% and applied 1 drop twice to four times daily for treatment of chronic feline herpes keratitis and may also be used prophylactically for feline herpes-virus (FHV) cats with a history of recurring ulcer.

포비돈요오드 준비 용품 및 원자재

원자재

준비 용품


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