ChemicalBook
Chinese English Japanese Germany Korea

헥사메틸포스포릭트리아미드

헥사메틸포스포릭트리아미드
헥사메틸포스포릭트리아미드 구조식 이미지
카스 번호:
680-31-9
한글명:
헥사메틸포스포릭트리아미드
동의어(한글):
헥사메틸포스포르아미드;헥사메틸포스포르아마이드(헥사메틸포스포르아미드);헥사메틸포스포릭트리아미드;헥사메틸포스포르아미드;헥사메틸포스포릭트라이아마이드
상품명:
Hexamethylphosphoramide
동의어(영문):
HPT;HMPA;HMPTA;HEMPA;ent50882;ENT 50882;ent50,882;ENT 50,882;hexamethyl;HEXAMETAPOL
CBNumber:
CB1177006
분자식:
C6H18N3OP
포뮬러 무게:
179.2
MOL 파일:
680-31-9.mol

헥사메틸포스포릭트리아미드 속성

녹는점
7 °C(lit.)
끓는 점
230-232 °C740 mm Hg(lit.)
밀도
1.03 g/mL at 25 °C(lit.)
증기 밀도
6.18 (vs air)
증기압
0.07 mm Hg ( 25 °C)
굴절률
n20/D 1.459(lit.)
인화점
222 °F
물리적 상태
liquid
냄새
Spicy odor (no threshold data)
수용성
Miscible
어는점
7℃
Merck
14,4725
BRN
1099903
안정성
Stable. Incompatible with strong acids, strong oxidizing agents.
InChIKey
GNOIPBMMFNIUFM-UHFFFAOYSA-N
CAS 데이터베이스
680-31-9(CAS DataBase Reference)
NIST
N,N,N',N',N",N'-Hexamethylphosphorotriamide(680-31-9)
EPA
Phosphoric triamide, hexamethyl-(680-31-9)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T
위험 카페고리 넘버 45-46
안전지침서 53-45-99
유엔번호(UN No.) 2810
WGK 독일 3
RTECS 번호 TD0875000
F 고인화성물질 8
위험 등급 6.1(b)
포장분류 III
HS 번호 29299090
유해 물질 데이터 680-31-9(Hazardous Substances Data)
독성 LD50 in male, female rats (mg/kg): 2650, 3360 orally (Gaines)
그림문자(GHS):
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H340 유전적인 결함을 일으킬 수 있음 (노출되어도 생식세포 유전독성을 일으키지 않는다는 결정적인 증거가 있는 노출경로가 있다면 노출경로 기재) 생식세포 변이원성 물질 구분 1A, 1B 위험
H350 암을 일으킬 수 있음 (노출되어도 암을 일으키지 않는다는 결정적인 증거가 있는 노출경로가 있다면 노출경로 기재) 발암성 물질 구분 1A, 1B 위험
예방조치문구:
P201 사용 전 취급 설명서를 확보하시오.
P308+P313 노출 또는 접촉이 우려되면 의학적인 조치· 조언를 구하시오.

헥사메틸포스포릭트리아미드 C화학적 특성, 용도, 생산

화학적 성질

colourless or light amber liquid with an aromatic spicy odour

화학적 성질

Hexamethylphosphoric triamide is a colorless liquid with a spicy odor.

용도

Aprotic solvent in organic synthesis. Solvent for polymers, gases; polymerization catalyst; thermal stabilizer in polystyrene; protective additive for polyvinyl and polyolefin resins against uv light degradation. De-icing additive for jet fuels. Chemosterilant for a number of insect pests; chemical mutagen.

일반 설명

Clear colorless to light amber liquid with a spicy odor.

공기와 물의 반응

Water soluble.

반응 프로필

Hexamethylphosphoramide may react with strong oxidizing agents and strong acids . Susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

위험도

Possible carcinogen. Toxic by skin contact. Combustible.

건강위험

The acute toxicity of hexamethylphosphoramide is low. HMPA can cause irritation upon contact with the skin and eyes. Hexamethylphosphoramide has been found to cause cancer in laboratory animals exposed by inhalation and meets the criteria for classification as an OSHA "select carcinogen." Chronic exposure to HMPA can cause damage to the lungs and kidneys. Reproductive effects in male animals treated with hexamethylphosphoramide have been observed. HMPA should be regarded as a substance with poor warning properties.

화재위험

Combustible liquid. Its decomposition at high temperatures or in a fire can produce phosphine, phosphorus oxides, and oxides of nitrogen, which are extremely toxic. Carbon dioxide or dry chemical extinguishers should be used for HMPA fires.

화재위험

Hexamethylphosphoramide is combustible.

인화성 및 폭발성

Combustible liquid. Its decomposition at high temperatures or in a fire can produce phosphine, phosphorus oxides, and oxides of nitrogen, which are extremely toxic. Carbon dioxide or dry chemical extinguishers should be used for HMPA fires.

잠재적 노출

Hexamethylphosphoric triamide is a material possessing unique properties and is widely used as a solvent in small quantities, in organic and organometallic reactions in laboratories. This is the major source of occu pational exposure to HMPA in the United States. It is also used as a processing solvent in the manufacture of aramid fibers. HMPA has been evaluated for use as an ultraviolet light absorber or inhibitor in polyvinylchloride formulations; as an additive for antistatic effects; as a flame retardant; and as a deicing additive for jet fuels. Hexamethylphosphoric triamide has also been extensively investigated as an insect chemosterilant.

Carcinogenicity

Hexamethylphosphoramide is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

저장

this compound should be handled only in a fume hood, using appropriate impermeable gloves and splash goggles to prevent skin and eye contact. Containers of this substance should be stored in secondary containers.

운송 방법

UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz ardous material, Technical Name Required

Purification Methods

The industrial synthesis is usually by treatment of POCl3 with excess of dimethylamine in isopropyl ether. Impurities are water, dimethylamine and its hydrochloride. It is purified by refluxing over BaO or CaO at about 4mm pressure in an atmosphere of nitrogen for several hours, then distilled from sodium at the same pressure. The middle fraction (b ca 90o) is collected, refluxed over sodium under reduced pressure under nitrogen and distilled. It is kept in the dark under nitrogen, and stored in solid CO2. It can also be stored over 4A molecular sieves. Alternatively, it is distilled under vacuum from CaH2 at 60o and is crystallised twice in a cold room at 0o, seeding the liquid with crystals obtained by cooling in liquid nitrogen. After about two-thirds are frozen, the remaining liquid is drained off [Fujinaga et al. Pure Appl Chem 44 117 1975]. For tests of purity see Fujinaga et al. in Purification of Solvents, Coetzee Ed., Pergamon Press, Oxford, 1982. For efficiency of desiccants in drying HMPA see Burfield and Smithers [J Org Chem 43 3966 1978, Sammes et al. J Chem Soc, Faraday Trans 1 281 1986]. [Beilstein 4 IV 284.] CARCINOGEN.

비 호환성

Incompatible (possibly violent reaction; fire and explosions) with oxidizers (chlorates, nitrates,peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.). Keep away from alkaline materials, chemi cally active metals, strong acids, strong bases.

폐기물 처리

Excess hexamethylphosphoramide and waste material containing this substance should be placed in an appropriate container, clearly labeled, and handled according to your institution's waste disposal guidelines.

법규

Environmental Protection Agency (EPA)
Clean Air Act
National Emissions Standards for Hazardous Air Pollutants: Listed as a hazardous air pollutant.
Comprehensive Environmental Response, Compensation, and Liability Act
Reportable quantity (RQ) = 1 lb.
Emergency Planning and Community Right-To-Know Act
Toxics Release Inventory: Listed substance subject to reporting requirements.

헥사메틸포스포릭트리아미드 준비 용품 및 원자재

원자재

준비 용품


헥사메틸포스포릭트리아미드 공급 업체

글로벌( 289)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19917 60
Hangzhou Bayee Chemical Co., Ltd.
0086-571-86990109; 0086-18605816692
0086-571-85775919 rachelhoo@bayeechem.com China 98 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 27142 58
Zhejiang ZETian Fine Chemicals Co. LTD
+86-18957127338
sales@zetchem.com CHINA 1797 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23964 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28237 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8260 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6370 58
Shandong chuangyingchemical Co., Ltd.
13156170209
sale@chuangyingchem.com CHINA 4419 58

헥사메틸포스포릭트리아미드 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved