N4-Acetylcytidine

N4-Acetylcytidine 구조식 이미지
카스 번호:
3768-18-1
상품명:
N4-Acetylcytidine
동의어(영문):
N-Acetylcytidine;Ac-rC;Acetylcytidine;rC(Ac);N4-Ac-Cr;N4-Ac-rC;ACETYL CYTOSINE;n-acetyl-cytidin;4-Acetylcytidine;N4-ACETYLCYTIDINE
CBNumber:
CB1207392
분자식:
C11H15N3O6
포뮬러 무게:
285.25
MOL 파일:
3768-18-1.mol

N4-Acetylcytidine 속성

녹는점
199 °C (dec.)(lit.)
밀도
1.72±0.1 g/cm3(Predicted)
저장 조건
Sealed in dry,Store in freezer, under -20°C
용해도
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
산도 계수 (pKa)
10.21±0.20(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 연한 노란색
CAS 데이터베이스
3768-18-1(CAS DataBase Reference)
NIST
Cytidine, n-acetyl-(3768-18-1)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn
위험 카페고리 넘버 20/21/22-36/37/38
안전지침서 36-36/37/39-26
WGK 독일 3
HS 번호 29335990
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
NFPA 704
0
3 0

N4-Acetylcytidine C화학적 특성, 용도, 생산

개요

N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. tRNA has been shown to be excreted in abnormal amounts in the urine of cancer patients. tRNA from neoplastic tissue had a much more rapid turnover rate than the tRNA from the corresponding normal tissue. Evidence indicates that methylation of tRNA occurs only after synthesis of the intact macromolecule. Because there are no specific enzyme systems to incorporate the modified nucleosides into the macromolecular nucleic acid, these nucleosides once released in the process of tRNA turnover cannot be reutilized, nor are they further degraded, but are excreted in urine.
N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.

용도

N4-Acetylcytidine (cas# 3768-18-1) is a nucleotide-derived metabolite used as biomarkers for diagnosis of inflammation-related diseases.

정의

ChEBI: N(4)-acetylcytidine is cytidine in which one of the exocyclic amino hydrogens is substituted by an acetyl group. It has a role as a metabolite. It is a member of cytidines, a member of acetamides and a secondary carboxamide.

N4-Acetylcytidine 준비 용품 및 원자재

원자재

준비 용품


N4-Acetylcytidine 공급 업체

글로벌( 204)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Zhejiang Hengkang Pharmaceutical Co., Ltd.
+86-576-83372028 +86-18868723926
bd1@hengkangpharm.cn China 119 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 15371 58
Shanghai Bojing Chemical Co.,Ltd.
+86-86-02137122233 +8613795318958
bj1@bj-chem.com China 298 55
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830
figo.gao@foxmail.com China 6992 58
Accela ChemBio Inc.
(+1)-858-699-3322
info@accelachem.com United States 19965 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845
sales@amoychem.com China 6387 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873
sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 47465 58
Antai Fine Chemical Technology Co.,Limited
18503026267
info@antaichem.com CHINA 9641 58

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