글루타치온에틸에스테르

글루타치온에틸에스테르
글루타치온에틸에스테르 구조식 이미지
카스 번호:
92614-59-0
한글명:
글루타치온에틸에스테르
동의어(한글):
글루타치온에틸에스테르
상품명:
Glutathione Ethyl Ester
동의어(영문):
GSH monoethylester;L-αGlu-L-Cys-Gly-OEt;H-GLU(CYS-GLY-OET)-OH;Glutathione Ethyl Ester;L-αGlu-L-Cys-Gly-Ethyl OH;γ-Glu-Cys-Gly-OEt, GSH-MEE;GLUTATHIONE MON ETHYL ESTER;Glutatione Reduced Ethyl Ester;GLUTATHIONE REDUCED FORM, ETHYL ESTE;Glycine, L-γ-glutamyl-L-cysteinyl-, 3-ethyl ester
CBNumber:
CB12130580
분자식:
C12H21N3O6S
포뮬러 무게:
335.38
MOL 파일:
92614-59-0.mol
MSDS 파일:
SDS

글루타치온에틸에스테르 속성

끓는 점
644.3±55.0 °C(Predicted)
밀도
1.314±0.06 g/cm3(Predicted)
저장 조건
-20°C
용해도
PBS (pH 7.2): 10 mg/ml; Water: 20 mg/ml
물리적 상태
결정성 고체
산도 계수 (pKa)
2.21±0.10(Predicted)
색상
White to off-white

안전

WGK 독일 3

글루타치온에틸에스테르 C화학적 특성, 용도, 생산

개요

Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH ethyl ester is a cell-permeable derivative of GSH that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH ethyl ester has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals.

Biochem/physiol Actions

Glutathione reduced ethyl ester (GSH-MEE) is a membrane/lipid permeable derivative of GSH that may be used to partially supplement the GSH supply within cells subjected to cysteine and/or GSH depletion. GSH-MEE is hydrolysed by intracellular esterases to release GSH, thereby increases the concentrations of intracellular GSH. It prevents the toxic effects of acetaminophen in animal cells. It protects human lymphoid cells and skin fibroblasts against the damage caused due to radiation.

글루타치온에틸에스테르 준비 용품 및 원자재

원자재

준비 용품


글루타치온에틸에스테르 공급 업체

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Aladdin Scientific
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Chemwill Asia Co.,Ltd. 86-21-51086038
chemwill_asia@126.com CHINA 23931 58

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