α-MSH (11-13) (free acid)
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α-MSH (11-13) (free acid) 속성
- 저장 조건
- -15°C
- InChI
- InChI=1S/C16H30N4O4/c1-10(2)13(16(23)24)19-14(21)12-7-5-9-20(12)15(22)11(18)6-3-4-8-17/h10-13H,3-9,17-18H2,1-2H3,(H,19,21)(H,23,24)/t11-,12-,13-/m0/s1
- InChIKey
- YSPZCHGIWAQVKQ-AVGNSLFASA-N
- SMILES
- C(O)(=O)[C@H](C(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)N
안전
α-MSH (11-13) (free acid) C화학적 특성, 용도, 생산
생물학적 활성
The C-terminal tripeptide α-MSH(11–13), also known as KPV (L-Lys-L-Pro-L-Val), exhibited anti-inflammation without induction of cutaneous pigmentation in a frog skin bioassay. The underlying molecular mechanisms of the α-MSH(11–13) anti-inflammatory properties have not been determined in detail. However, they are related to an inhibition of TNF-α, IL-6, and nitric oxide production in a model of LPS-stimulated murine microglial cell culture[1]. Furthermore, it has been recently shown that α-MSH(11–13) reduces activation of NF-κB and decreases its translocation into the nucleus by interaction with importin family proteins.α-MSH (11-13) (free acid) 준비 용품 및 원자재
원자재
준비 용품
α-MSH (11-13) (free acid) 공급 업체
글로벌( 67)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Weimiao Import and Export Trade Co., Ltd. | +undefined19948166995 |
sale01@hbweimiao.com | China | 64 | 58 |
| Hebei Xunou new energy Technology Co., LTD | +undefined17531957005 |
xunou8@hbxunou.com | China | 36 | 58 |
| Wuhan Xinhao Biotechnology Co., Ltd | +86-18120578002 +86-18120578002 |
xinhao-6@xinhaoshengwu.com | China | 350 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 |
xinshengkeji@xsmaterial.com | China | 1100 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
| Hebei Anlijie Biotechnology Co., Ltd | +8619031013551 |
ably@aljbio.com | China | 177 | 58 |
| Shijiazhuang Saixin Technology Co., Ltd. | +86-16632312509 +86-16632315022 |
saixinkeji@aliyun.com | China | 90 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 616 | 58 |
| Sigma Audley | +86-18336680971 +86-18126314766 |
nova@sh-teruiop.com | China | 524 | 58 |