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(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID 구조식 이미지

카스 번호:: 16626-02-1

상품명:: (S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID

동의어(영문):: H-L-Trp(5-F)-OH*H2O;L-5-FLUOROTRYPTOPHAN;5-FLUORO-L-TRYPTOPHAN;H-5-FLUORO-TRP-OH H2O;Tryptophan Impurity 54;5-fluoro-L-tryptophans;L-Tryptophan, 5-fluoro-;5-Fluoro-tryptophan monohydrate;L-5-fluorotryptophan monohydrate;5-FLUORO-L-TRYPTOPHAN MONOHYDRATE

CBNumber:: CB1274150

분자식:: C11H11FN2O2

포뮬러 무게:: 222.22

MOL 파일:: 16626-02-1.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 74

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID 속성

녹는점: 238-239 °C

끓는 점: 450.7±45.0 °C(Predicted)

밀도: 1.442±0.06 g/cm3(Predicted)

저장 조건: 2-8°C

산도 계수 (pKa): 2.21±0.10(Predicted)

BRN: 5052680

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

안전지침서	22-24/25
WGK 독일	3
F 고인화성물질	10
HS 번호	2933998090

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P261	분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID C화학적 특성, 용도, 생산

용도

Exogenous 5-fluoro-Trp is incorporated into proteins in normal protein synthesis. Since ¹⁹F is a useful reporter group, this provides a method for studying enzyme mechanisms by NMR.

Biochem/physiol Actions

5-Fluoro-Trp is nonspecifically cytotoxic. It is believed this is due to malfunctioning enzymes that have had replacements of Trp residues by 5-fluoro-Trp. However, at least one case is known where 5-fluoro-Trp substitution leads to significantly greater catalytic activity.

Purification Methods

Recrystallise it from EtOH, aqueous EtOH or AcOH. Also purify it by passage through a Dowex AG1x2 (acetate form) column and recrystallise the L-enantiomer (from enzymic enrichment) from H2O/EtOH, m 158-163o(dec), [] D -8.3o (c 2.5, N NaOH). [Coy et al. Biochemistry 13 3550 1974, Beilstein 22/14 V 116.]

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID 준비 용품 및 원자재

원자재

준비 용품

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID 공급 업체

글로벌( 74)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	6992	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
GL Biochem(Binhai) Ltd.	+86-021-61263370 +8615301650015	wuqiuyan@glschina.com	China	2975	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4022	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9923	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
DONBOO AMINO ACID COMPANY	+8613063595538	donboo@donboo.com	China	9365	58

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID 관련 검색:

감마-아미노-N-부티르 산 Azelaic acid 5-Hydroxymethylfurfural Isoimperatorin Phosphatidylserine Soapnut Extract (-)-Huperzine A L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE Astaxanthin (2S)-2-Amino-3-(6-fluoro-1H-indol-3-yl)propionic acid,(S)-2-AMINO-3-(6-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID (S)-2-AMINO-3-(4-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID (S)-2-AMINO-3-(5-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID 7-CHLORO-L-TRYPTOPHAN (S)-2-AMINO-3-(4-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID H-TRP-GLY-OH (2S)-2-amino-3-(5-bromo-1H-indol-3-yl)propanoic acid 6-broMo-L-tryptophan H-TRP(BOC)-OH