NSC 150117 hydrochloride
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NSC 150117 hydrochloride 속성
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 용해성10mg/mL, 투명
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
안전
| WGK 독일 | 3 |
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NSC 150117 hydrochloride C화학적 특성, 용도, 생산
용도
(E/Z)-BCI hydrochloride has been used:- to evaluate the role of the Duox-H2O2-Dusp6 derepression signaling pathway in heart regeneration
- as an MKP-1 inhibitor to investigate the role of MKP-1 on bexarotent-induced effects
- as a dual specificity phosphatase 6 (DUSP6) inhibitor to study its effects on the proliferation of SKOV3 cells
Biochem/physiol Actions
BCI is an allosteric inhibitor of Dusp6 that acts within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also hyperactivates FGF signaling, since Dusp6 functions as a feedback regulator of FGF signaling.NSC 150117 hydrochloride 준비 용품 및 원자재
원자재
준비 용품
NSC 150117 hydrochloride 공급 업체
글로벌( 17)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9709 | 58 |
| Shanghai Han-Xiang Chemical Co., Ltd. | 15971444841 |
amber@biochempartner.com | China | 3063 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | 0519-85788828 13775037613 |
sales@chemrenpharm.com | China | 3553 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 |
hongquchem@qq.com | China | 5132 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 |
psaitong@jm-bio.com | China | 29778 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24131 | 58 |