GHRELIN (RAT)

GHRELIN (RAT) 구조식 이미지
카스 번호:
258338-12-4
상품명:
GHRELIN (RAT)
동의어(영문):
GR-28;Rat ghrelin;GHRELIN (RAT);Rat ghrelin-28;GHRELIN (RAT) USP/EP/BP;Ghrelin, rat (n-octanoyl);Ghrelin (Rattus norvegicus);GHRELIN, RAT, SER(N-OCTANOYL);M.W. 3314.83 C147H245N45O42;GHRELIN (RAT) TRIFLUOROACETATE
CBNumber:
CB1302952
분자식:
C147H245N45O42
포뮬러 무게:
3314.79
MOL 파일:
258338-12-4.mol

GHRELIN (RAT) 속성

밀도
1.49±0.1 g/cm3(Predicted)
RTECS 번호
LY8965000
저장 조건
-15°C
물리적 상태
동결건조된 분말
색상
하얀색
수용성
Soluble to 1 mg/ml in water

안전

WGK 독일 3
HS 번호 2937190000

GHRELIN (RAT) C화학적 특성, 용도, 생산

용도

Ghrelin rat has been used for intraperitoneal injections, and microinjections in rats to study its effects on celiac disease, and passive avoidance learning (PAV) and spatial learning, respectively. It has also been used for intracerebroventricular injection in rats to study its influence on penicillin-induced epileptiform activity in rat.

일반 설명

Ghrelin is a gut-brain orexigenic peptide that functions in hunger signaling. This peptide is prominently synthesized by stomach and transported to brain. However, a specific subset of hypothalamic neurons also produces this peptide. It is expressed in gastrointestinal tract, hypothalamic arcuate nucleus, pituitary, kidney, liver, heart, lung and adipose tissue This peptide is composed of 28 amino acids, and its Ser3 residue is N-octanoylated.

Biochem/physiol Actions

Ghrelin acts as a ligand for G-protein coupled receptor, GHS-R1A (growth hormone secretagogue receptor), and controls energy utilization and feeding. This peptide is involved in enhancing the value of rewarding foods, drugs and alcohol. In rats with diabetes, the expression of ghrelin increased as a result of cachexia. In rats with ovariectomy, the expression of this peptide decreased in the endometrium. This peptide controls cognitive functions and has neuroprotective roles in neurodegenerative disorders. In cultured cortical neuronal networks, ghrelin increases the rate of synapse formation and activity development.

GHRELIN (RAT) 준비 용품 및 원자재

원자재

준비 용품


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