Nonapeptide-1

Nonapeptide-1 구조식 이미지
카스 번호:
158563-45-2
상품명:
Nonapeptide-1
동의어(영문):
melanostatine;Melanostatine-5;Melitan;Neptide-1;Jiupeptide-1;NONAPEPTIDE-1;Metanostatine-5;Melitane / Nonapeptide-1;hexapeptide-2/Dermostatyl;4-Hydroxypyridine 626-64-2
CBNumber:
CB13052001
분자식:
C61H87N15O9S
포뮬러 무게:
1206.5
MOL 파일:
158563-45-2.mol

Nonapeptide-1 속성

밀도
1.38±0.1 g/cm3(Predicted)
용해도
soluble in water(≥0.1g/ml)
산도 계수 (pKa)
13.32±0.46(Predicted)
색상
white or off-white powder
InChIKey
KNFLNGRLKALWRF-LDXSYGEZSA-N

안전

Nonapeptide-1 C화학적 특성, 용도, 생산

개요

Nonapeptide-1 is a skin lightening peptide, derived from the melanocyte stimulating hormone (MSH). It prevents the activity of tyrosine in the melanocytes, melanin synthesis inhibition and helps to even out your skin tone by lessening hyper-pigmentation. This process reduces the formation of unwanted pigmentation, allowing for the control over skin tone and brown spots.

정의

Nonapeptide-1 is one skin whitening nonapeptide. It can be applied to various kinds of whitening or spot corrective products.

Biological Functions

1. Inhibit melanin synthesis by interfering with the action of tyrosinase in melanocytes. Reduce hyperpigmentation and lighten darker areas that have been damaged by the sun and certain diseases.2. Interfer with melanocyte stimulating hormone (MSH). MSH increases during pregnancy, as a result of certain medical conditions (e.g. diabetes, Addison’s disease), and as a result of excessive sun exposure.3. Nonapeptide-1, at a concentration of 200 ug/mL, is capable of fully inhibiting the synthesis of melanin in fungi.4. At 100 micromolar concentration, nonapeptide-1 can inhibit 25-35% of tyrosinase activity in animal models and can reduce the melanin content of melanocytes by 27-43%

Biotechnological Applications

Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Reduces synthesis of melanin and helps decrease skin pigmentation to a substantial degree[1].

부작용

May cause drowsiness, dizziness, hypotension, or a headache as side-effects when using Nonapeptide-1 Topical medicine. Patients not drink alcohol with medicines as alcohol intensifies drowsiness side-effects.

Nonapeptide-1 준비 용품 및 원자재

원자재

준비 용품


Nonapeptide-1 공급 업체

글로벌( 262)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Shanghai Getian Industrial Co., LTD
+86-15373193816 +86-15373193816
mike@ge-tian.com China 272 58
Cellmano Biotech Limited
0551-65326643 18156095617
info@cellmano.com China 999 58
Xinxiang Hongqi District Houyuan Trading Co.,Ltd
+86-0373-3695376 +86-13937349994
HYJM@houyuanjm.com China 300 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971
deasea125996@gmail.com China 2503 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8474 58
Hantai Biomedical Group Co. LTD
+8618819265912
id002@cnhantide.com China 37 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490
info@gihichemicals.com China 50000 58
Wuhan Marco Pharmaceutical Technology Co., Ltd.
+86-86-18572802410 +8618572802410
sales@marcopht.com China 55 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578
sales@hbmojin.com China 12456 58
Shanghai UCHEM Inc.
+862156762820 +86-13564624040
sales@myuchem.com China 6710 58

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