아데닌

아데닌
아데닌 구조식 이미지
카스 번호:
73-24-5
한글명:
아데닌
동의어(한글):
6-아미노푸린;아데닌
상품명:
Adenine
동의어(영문):
9H-Purin-6-amine;Adenin;6-AMINOPURINE;Vitamin B4;7H-PURIN-6-AMINE;Ade;ANE;Purin-6-amine;1H-PURIN-6-AMINE;6-Amino-9H-purine
CBNumber:
CB1323708
분자식:
C5H5N5
포뮬러 무게:
135.13
MOL 파일:
73-24-5.mol
MSDS 파일:
SDS

아데닌 속성

녹는점
>360 °C (lit.)
끓는 점
238.81°C (rough estimate)
밀도
1.3795 (rough estimate)
굴절률
1.7000 (estimate)
인화점
220°C
저장 조건
2-8°C
용해도
0.5 M HCl: 용해성 20mg/mL, 등급 III, 무색 ~ 희미한 노란색 또는 황갈색
물리적 상태
액체 또는 고체
산도 계수 (pKa)
4.12(at 25℃)
색상
무색투명~연황색
냄새
냄새 없는
pH 범위
7
수용성
0.5g/L(20℃)
승화점
220 ºC
Merck
14,152
BRN
5777
안정성
안정적인. 습기에 민감합니다. 강한 산화제와 호환되지 않습니다.
InChIKey
GFFGJBXGBJISGV-UHFFFAOYSA-N
LogP
-0.090
CAS 데이터베이스
73-24-5(CAS DataBase Reference)
NIST
Adenine(73-24-5)
EPA
Adenine (73-24-5)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,Xi
위험 카페고리 넘버 22-20/21/22
안전지침서 26-36
유엔번호(UN No.) UN 2811 6.1/PG 3
WGK 독일 3
RTECS 번호 AU6125000
F 고인화성물질 8-10-23
TSCA Yes
위험 등급 6.1
포장분류 III
HS 번호 29335990
독성 LD50 orally in rats: 745 mg/kg (Philips)
기존화학 물질 KE-29916
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H301 삼키면 유독함 급성 독성 물질 - 경구 구분 3 위험 GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
예방조치문구:
NFPA 704
1
2 0

아데닌 MSDS


6-Aminopurine

아데닌 C화학적 특성, 용도, 생산

개요

찬물에는 잘 녹지 않으며 양쪽성 물질로 산과 염기 모두에 잘 녹는다. 염산을 가하여 180~200 °C로 가열하면 분해된다. 아질산과 작용하면 하이포잔틴이 되고, 산화되면 요소를 생성한다. 산 또는 염기와 반응하여 생성된 염을 이용하여 정제할 수 있다.

개요

adenine is one of the purine nitrogenous bases that composes DNA and RNA; composed of two carbon–nitrogen rings. Adenine bonds with thymine in DNA and with uracil in RNA (see base pairing rule); it is also a major component of other molecules such as adenosine triphosphate.

화학적 성질

Adenine is a prominent member of the family of naturally occurring purines. Adenine occurs not only in ribonucleic acids (RNA), and deoxyribonucleic acids (DNA), but in nucleosides, such as adenosine, and nucleotides, such as adenylic acid, which may be linked with enzymatic functions quite apart from nucleic acids. Adenine, in the form of its ribonucleotide, is produced in mammals and fowls endogenously from smaller molecules and no nutritional essentiality is ascribed to it. In the nucleosides, nucleotides, and nucleic acids, the attachment or the sugar moiety is at position 9.
The purines and pyrimidines absorb ultraviolet light readily, with absorption peaks at characteristic frequencies. This has aided in their identification and quantitative determination.

물리적 성질

Adenine is a white to almost white crystalline powder that is an important biological compound found in deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and adenosine triphosphate (ATP). It was once commonly referred to as vitamin B4 but is no longer considered a vitamin. Adenine is derived from purine. Purine is a heterocyclic compound.

역사

Adenine is one of the two purines found in DNA and RNA. The other is guanine. Adenine and guanine are called bases in reference to DNA and RNA. A nucleic acid base attached to ribose forms a ribonucleoside. Adenine combined with ribose produces the nucleoside adenosine.

용도

Adenine is used as an active component of boron-deficient media to grow yeast in order to assess whether yeast growth is stimulated by boron. It is useful as a local antiseptic and vitamin B4. Further, it is used in the microbial determination of niacin. It is also employed as a food supplement for adult rats to investigate the effects of dietary adenine overload. In addition to this, it is used in the production of nucleotides of the nucleic acids.

정의

ChEBI: Adenine is the parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6. It has a role as a human metabolite, a Daphnia magna metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purine nucleobase and a member of 6-aminopurines. It derives from a hydride of a 9H-purine.

주요 응용

Widespread throughout animal and plant tissues combined with niacinamide, d-ribose, and phosphoric acids; a constituent of nucleic acids and coenzymes, such as codehydrase I and II, adenylic acid, coa laninedehydrase. It is used in microbial determination of niacin; in research on heredity, virus diseases, and cancer.

일반 설명

Adenine is a purine nucleobase. It is part of DNA, and RNA. Adenine is also a component of cofactors (NAD, FAD) and signaling molecules (cAMP). It is a nitrogenous base found in DNA and RNA. It is also a constituent of certain coenzymes and when combined with the sugar ribose it forms the nucleoside adenosine found in AMP, ADP, and ATP. Adenine has a purine ring structure. It is one of the major component bases ofnucleotides and the nucleic acidsDNA and RNA.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.

Purification Methods

Crystallise adenine from distilled water. [Beilstein 26 III/IV 3561.]

아데닌 준비 용품 및 원자재

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