Methyl phenylacetate

Methyl phenylacetate 구조식 이미지
카스 번호:
101-41-7
상품명:
Methyl phenylacetate
동의어(영문):
Methyl 2-phenylacetate;Methylphenylacetat;PHENYLACETIC ACID METHYL ESTER;2-phenylpropanoate;Methyl benzeneacetate;FEMA 2733;Mephaneine;METHYL A-TOLUATE;METHYLPAROXETINE;METHYL-PHENYLACETAT
CBNumber:
CB1333473
분자식:
C9H10O2
포뮬러 무게:
150.17
MOL 파일:
101-41-7.mol
MSDS 파일:
SDS

Methyl phenylacetate 속성

녹는점
107-115 °C
끓는 점
218 °C (lit.)
밀도
1.066 g/mL at 20 °C (lit.)
증기압
16.9-75Pa at 20℃
FEMA
2733 | METHYL PHENYLACETATE
굴절률
n20/D 1.503(lit.)
인화점
195 °F
저장 조건
Store below +30°C.
용해도
클로로포름(약간 용해됨), 메탄올(약간 용해됨)
색상
무색
냄새
디프로필렌 글리콜 중 10.00%. 달콤한 꽃 꿀 향신료 밀랍 아몬드
?? ??
수용성
물과 섞일 수 있습니다.
Merck
14,7268
JECFA Number
1008
BRN
878795
안정성
안정적인. 타기 쉬운. 강한 산화제, 강한 염기와 호환되지 않습니다.
InChIKey
CRZQGDNQQAALAY-UHFFFAOYSA-N
LogP
1.91-2.09 at 21.9-25℃
CAS 데이터베이스
101-41-7(CAS DataBase Reference)
NIST
Benzeneacetic acid, methyl ester(101-41-7)
EPA
Methyl phenylacetate (101-41-7)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn
위험 카페고리 넘버 21-R21
안전지침서 23-24/25
WGK 독일 2
RTECS 번호 AJ3175000
TSCA Yes
HS 번호 29163500
유해 물질 데이터 101-41-7(Hazardous Substances Data)
독성 The acute oral LD50 in rats was reported as 2.55 g/kg (1.67-3.43 g/kg) and the acute dermal LD50 in rabbits as 2.4 g/kg (0.15-4.7 g/kg) (Moreno, 1974).
기존화학 물질 KE-24800
그림문자(GHS): GHS hazard pictogramsGHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H227 가연성 액체 인화성 액체 구분 4 경고 P210, P280, P370+P378, P403+P235,P501
H303 삼키면 유해할 수 있음 급성 독성 물질 - 경구 구분 5 P312
예방조치문구:
P403+P235 환기가 잘 되는 곳에 보관하고 저온으로 유지하시오.
NFPA 704
2
0 0

Methyl phenylacetate MSDS


Methyl phenylacetate

Methyl phenylacetate C화학적 특성, 용도, 생산

화학적 성질

Methyl phenylacetate is a clear colorless liquid that is only slightly soluble in water, but very soluble in most organic solvents. It has a strong odor similar to honey. The odor is so strong that recommended smelling is of a solution with 10% or less methyl phenyl acetate. This compound also naturally occurs in brandy, capsicum, coffee, honey, pepper and some wine.

출처

Reported found in cocoa, coffee, strawberry, pineapple, pepper, hop oil, cognac, peanut, honey, starfruit, Bourbon vanilla, mountain papaya, roasted chicory root and rooibus tea (Aspalathus linearis).

용도

Methyl phenylacetate is utilized for partition coefficient measurement experiments. It is mainly used in the flavor industry and in perfumes to impart honey scents. Further, it acts as a precursor to prepare synthetic perfumes. It acts as an acylating agent and involved in the enantioselective acylation of beta-lactam intermediate using penicillin G amidase.

주요 응용

Methyl Phenylacetate is used as a reagent in the synthesis of various organic reactions, one of which is the synthesis of Vulpinic Acid; a lichen metabolite with anti-inflammatory properties. It is also used in the formulation of edible flavors, for the preparation of honey, chocolate, tobacco and other flavors; it can also be used in daily chemical flavors for the preparation of rose, oriental flavors and other flavors. IFRA has no restrictions.

제조 방법

Methyl phenylacetate is synthesized from phenylacetonitrile by hydrolysis and esterification. Put methanol into a dry glass-lined reaction pot, stir and cool to below 30°C, add sulfuric acid dropwise, heat up to 90°C after adding, and start adding phenylacetonitrile dropwise, control the temperature at about 95°C, and finish adding in 1.5h. After reacting at 95-100 °C for 6 h, it was cooled to below 40 °C and diluted with water equivalent to about 0.6 times the reaction solution. The acid water was separated by standing, and a saturated sodium carbonate solution was added for neutralization and washing, and the aqueous layer was discarded. It is dehydrated with anhydrous calcium chloride and fractionated under reduced pressure to obtain methyl phenylacetate with a yield of 80%.

정의

ChEBI: Methyl benzeneacetate is a member of benzenes. It is a flavoring ingredient. Odoriferous constituent of many plants. It is generally found in brandy, capsicum, honey, pepper, some wine, coca and coca products.

일반 설명

Methyl phenylacetate has been identified in the volatile fraction of beewax absolute oil, dried fruiting bodies of Boletus auripes, Chinese fermented black soybeans and peated malt.

Safety Profile

Moderately toxic by ingestion and skin contact. A skin irritant. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTERS.

Methyl phenylacetate 준비 용품 및 원자재

원자재

준비 용품


Methyl phenylacetate 공급 업체

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