락톤
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락톤 속성
- 녹는점
- 229-231 °C(lit.)
- 끓는 점
- 310.05°C (rough estimate)
- 밀도
- 1.2196 (rough estimate)
- 굴절률
- 1.5557 (estimate)
- 저장 조건
- -20°C
- 용해도
- DMSO: 용해될 수 있다
- 물리적 상태
- 가루
- 색상
- 하얀색
- Merck
- 14,9735
- BRN
- 221723
- CAS 데이터베이스
- 3902-71-4
- IARC
- 3 (Vol. 40, Sup 7) 1987
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | C | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 34-40 | ||
| 안전지침서 | 26-36/37/39-45 | ||
| 유엔번호(UN No.) | UN 1759 8/PG 1 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | LV1576000 | ||
| F 고인화성물질 | 8-10 | ||
| TSCA | Yes | ||
| 위험 등급 | 8 | ||
| 포장분류 | III | ||
| HS 번호 | 29322985 | ||
| 기존화학 물질 | KE-34519 |
락톤 C화학적 특성, 용도, 생산
화학적 성질
White to slightly beige crystalline powder용도
Trioxsalen has been used:- to induce small deletion mutations in worms
- in combination with ultraviolet A (UVA)
- to induce interstrand crosslinks (ICLs) in DNA
- for the preparation and photoactivation of trimethyl psoralen
Indications
Trioxsalen (Trisoralen) followed by UVA exposure is used to repigment vitiliginous areas and in photochemotherapy.정의
ChEBI: 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phot therapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermi .Purification Methods
Purify trioxsalen by recrystallisation from CHCl3. If too impure, it is fractionally crystallised from CHCl3/pet ether (b 30-60o) using Norit and finally crystallised from CHCl3 alone to give colourless prisms, m 234.5-235o. It is a photosensitiser so it should be stored in the dark. [UV: Kaufmann J Org Chem 26 117 1961, Baeme et al. J Chem Soc 2976 1949, Beilstein 19/4 V 472.]락톤 준비 용품 및 원자재
원자재
아세트초산에틸
에틸알코올
아세톤
탄산 칼륨
1,3- 벤젠, 2- 메틸
설파믹산
메틸알콜
수산화나트륨
N,N-디에틸아닐린
황산마그네슘
1,2,3-Tribromopropane
황산 칼륨
염산
나트륨
2H-1-Benzopyran-2-one, 7-[(2-chloro-2-propenyl)oxy]-4,8-dimethyl-
7-ALLYLOXY-4,8-DIMETHYL-CHROMEN-2-ONE
6-allyl-7-hydroxy-4,8-dimethyl-2H-chromen-2-one
7-HYDROXY-4,8-DIMETHYLCOUMARIN
준비 용품
락톤 공급 업체
글로벌( 122)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 |
1012@dideu.com | China | 3422 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 29271 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 |
info@afinechem.com | CHINA | 15377 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 |
info@finetechnology-ind.com | China | 9702 | 58 |
| Alfa Chemistry | +1-5166625404 |
Info@alfa-chemistry.com | United States | 21317 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
1026@dideu.com | China | 9116 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
락톤 관련 검색:
락톤
Psoralen
3-(HYDROXYMETHYL)-2,5,9-TRIMETHYL-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE
PSORALEN-C 6 CEP
Trioxsalen, 4-Aminomethyl-, HCl
3-(2-HYDROXY-ETHOXYMETHYL)-2,5,9-TRIMETHYL-FURO[3,2-G]CHROMEN-7-ONE
3-CHLOROMETHYL-2,5,9-TRIMETHYL-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE
PSORALEN-C 2 CEP
3-(6-HYDROXYHEXYL)METHYL-2,5,9-TRIMETHYL-7H-FURO[3,2-G]-[1]BENZOPYRAN-7-ONE
TRIOXSALEN(RG)
1-(O-B-D-GALACTOPYRANOSYL)*METHYL TRIOXSALEN
1-(O-BETA-D)-GALACTOPYRANOSYL)METHYL TRIOXSALEN
1-(O-?-D)-GALACTOPYRANOSYL)METHYL TRIOXSALEN
1,15-bis(4'-trioxsalen)-2,6,10,14-tetramethyl-2,6,10,14-tetrazapentadecane
TRIOXSALEN, 4'-AMINOMETHYL-, HYDROCHLORIDE
TRIOXSALEN, 4'-HYDROXYMETHYL-
3-(2-AMINOOXY-ETHOXYMETHYL)-2,5,9-TRIMETHYL-FURO[3,2-G]CHROMEN-7-ONE
3-(2-AMINO-ETHOXYMETHYL)-2,5,9-TRIMETHYL-FURO[3,2-G]CHROMEN-7-ONE