4-아미노-m-크레솔
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4-아미노-m-크레솔 속성
- 녹는점
- 176-179 °C (lit.)
- 끓는 점
- 229.26°C (rough estimate)
- 밀도
- 1.0877 (rough estimate)
- 굴절률
- 1.5380 (estimate)
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 메탄올에 용해됨
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 10.34±0.18(Predicted)
- 색상
- 갈색
- 수용성
- 불용성
- BRN
- 2078803
- InChIKey
- QGNGOGOOPUYKMC-UHFFFAOYSA-N
- LogP
- 0.51 at 22℃
- CAS 데이터베이스
- 2835-99-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-36/37/38-20/21/22 | ||
| 안전지침서 | 26-37/39-36/37/39-36-24/25 | ||
| 유엔번호(UN No.) | UN3077 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | GO6826000 | ||
| F 고인화성물질 | 8-10-23 | ||
| TSCA | Yes | ||
| 위험 등급 | 9 | ||
| 포장분류 | III | ||
| HS 번호 | 29222900 | ||
| 기존화학 물질 | 2002-3-2144 |
4-아미노-m-크레솔 C화학적 특성, 용도, 생산
개요
4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).화학적 성질
Light gray powder용도
4-Amino-3-methylphenol is a useful reagent for the synthesis of piperidine (piperazine)-amide substituted derivatives as multi-target antipsychotics.4-Amino-3-methylphenol was used in synthesis of a new type of tweezer-molecule in which a strongly preferred binding conformation is generated by convergent, intramolecular hydrogen bonding.
정의
ChEBI: A substituted aniline in which the aniline ring carries 4-hydroxy and 6-methyl substituents; a urinary metabolite of lidocaine.주요 응용
4-Amino-m-cresol is used as an oxidative hair dye at a maximum concentration of 1.5% after mixing with peroxide.일반 설명
4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).Synthesis
The synthesis of 4-Amino-3-methylphenol is as follows:A mixture of the para-benzoquinone mono-oxime (1.26 mmol),SnCl2 (0.72 g, 3.80 mmol), 20 mL of CH2Cl2, and 0.2 mL of concentrated HCl, was heated to reflux for 16 h. The CH2Cl2 was removed under reduced pressure, and the residue was dissolved in ethyl acetate and washed with concentrated aqueous NaHCO3. The organic layer was dried over anhydrous Na2SO4 and the filtrate was concentrated under reduced pressure to afford the solid product.
Purification Methods
Crystallise it from 50% EtOH. [Beilstein 13 H 593, 13 IV 1698.]4-아미노-m-크레솔 준비 용품 및 원자재
원자재
준비 용품
4-아미노-m-크레솔 공급 업체
글로벌( 401)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Taixing Foreign Trade Nanjing Co., Ltd. | +8613182976929 |
sales@tx-chem.com | China | 120 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-13102810335 |
admin@hbsaisier.cn | China | 626 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10248 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |