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GM 1489

GM 1489 구조식 이미지

카스 번호:: 171347-75-4

상품명:: GM 1489

동의어(영문):: (3R)-3-[[[(1S)-1-(1H-indol-3-ylmethyl)-2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]carbonyl]-5-methyl-hexanoicacid;Hexanoic acid, 3-[[[(1S)-1-(1H-indol-3-ylmethyl)-2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]carbonyl]-5-methyl-, (3R)-

CBNumber:: CB14666490

분자식:: C27H33N3O4

포뮬러 무게:: 463.57

MOL 파일:: 171347-75-4.mol

속성

안전

용도

공급 업체 7

GM 1489 속성

끓는 점: 795.4±60.0 °C(Predicted)

밀도: 1.203±0.06 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 0.2 mg/ml

물리적 상태: 결정성 고체

산도 계수 (pKa): 4.71±0.10(Predicted)

안전

GM 1489 C화학적 특성, 용도, 생산

개요

GM 1489 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with K_i values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively. It reduces 5-aza-2''-deoxycytidine-induced increases in MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, and MMP-14 expression as well as cell invasion in AsPC-1, BxPC-3, Hs766T, MiaPaCa2, and PANC-1 cancer cells. Topical administration of GM 1489 (100 μg) inhibits increases in ear thickness and epidermal hyperplasia induced by phorbol 12-myristate 13-acetate (TPA; ) and phorbol dibutyrate (PdiBu) in mice.

GM 1489 준비 용품 및 원자재

원자재

준비 용품

GM 1489 공급 업체

글로벌( 7)공급 업체

공급자	전화	이메일	국가	제품 수	이점
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
Shanghai Yiyan Biotechnology Co. , Ltd.	021-69985186 13611928337	3427709316@qq.com	China	7984	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	5141	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58