POMALIDOMIDE-PEG1-CO2H
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POMALIDOMIDE-PEG1-CO2H 속성
- 끓는 점
- 726.2±60.0 °C(Predicted)
- 밀도
- 1.508±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 물리적 상태
- 분말 또는 결정
- 산도 계수 (pKa)
- 4.29±0.10(Predicted)
안전
POMALIDOMIDE-PEG1-CO2H C화학적 특성, 용도, 생산
용도
Protein degrader builiding block Pomalidomide-PEG1-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.POMALIDOMIDE-PEG1-CO2H 준비 용품 및 원자재
원자재
준비 용품
POMALIDOMIDE-PEG1-CO2H 공급 업체
글로벌( 39)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 |
3207347307@qq.com | CHINA | 1238 | 58 |
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13783527580 |
Lingzhiyue@aliyun.com | China | 3138 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 |
sales@bicbiotech.com | China | 6000 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 |
info@chemextension.com | China | 42057 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 |
1924344760@confluore.cn | China | 2893 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 |
han_yajun@dctc.daicel.com | China | 6818 | 65 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 18112977050 |
cb6@aikonchem.com | China | 16687 | 50 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
POMALIDOMIDE-PEG1-CO2H 관련 검색:
Pomalidomide-PEG4-CO2H
Pomalidomide-PEG3-CO2H
POMALIDOMIDE-PEG2-CO2H
Pomalidomide-PEG1-azide
Pomalidomide-O-C4-NH2
Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]-
Pomalidomide-PEG3-N3
Pomalidomide-PEG6-butyl iodide
Pomalidomide-PEG5-CO2H
E3 ligase Ligand-Linker Conjugates 50
Pomalidomide-PEG3-Amine HCl salt
E3 Ligase Ligand-Linker Conjugates 1
4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
E3 Ligase Ligand-Linker Conjugates 22
Pomalidomide-PEG2-butyl iodide
Pomalidomide-PEG4-azide
Pomalidomide-PEG2-N3
POMALIDOMIDE-PEG1-ALKYNE