다이하이드로미리세틴

다이하이드로미리세틴
다이하이드로미리세틴 구조식 이미지
카스 번호:
27200-12-0
한글명:
다이하이드로미리세틴
동의어(한글):
다이하이드로미리세틴
상품명:
Dihydromyricetin
동의어(영문):
ampeloptin;AMPELOPSIN;Two hydrogenMyricetin;vine tea extract dihydromyricetin;3,3’,4’,5,5’,7-hexahydroxy-flavanon;DihydroMyricetin, froM Myrica rubra;3,3’,4’,5,5’,7-hexahydroxy-2,3-dihydroflavanonol;2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on;3,3',4',5,5;,(2r-trans)-
CBNumber:
CB1670507
분자식:
C15H12O8
포뮬러 무게:
320.25
MOL 파일:
27200-12-0.mol
MSDS 파일:
SDS

다이하이드로미리세틴 속성

저장 조건
-20°C
용해도
DMSO: ≥5mg/mL(가온)
물리적 상태
가루
끓는 점
780.7±60.0 °C(Predicted)
밀도
1.808±0.06 g/cm3(Predicted)
녹는점
239-241 °C
산도 계수 (pKa)
7.38±0.60(Predicted)
색상
흰색에서 베이지색
안정성
흡습성
InChI
InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1
InChIKey
KJXSIXMJHKAJOD-LSDHHAIUSA-N
SMILES
[C@H]1(C2=CC(O)=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O
LogP
1.230 (est)
CAS 데이터베이스
27200-12-0

안전

안전지침서 24/25
WGK 독일 3
HS 번호 29329990

다이하이드로미리세틴 C화학적 특성, 용도, 생산

개요

Dihydromyricetin (DHM), also known as ampelopsin, is a natural flavonoid compound, which is found in large quantities in Asian plant species. One of them – Hovenia dulcis – is known for centuries in traditional Chinese medicine as a cure for alcohol poisoning and hangover (Liang et al. 2014). DHM is sold as a supplement and is commonly marketed as a treatment for hangovers due to its ability to reduce blood alcohol levels and projected hepatoprotective properties.
Dihydromyricetin had beneficial effects on health such as antimicrobial, anti-inflammatory,antioxidative, anticancer, lipid and glucose metabolism-regulatory activities,and cell death-mediating without or with minimum adverse effects on normal cells. And most importantly, DHM has been shown to provide significant hepatoprotective effects. Its positive influence on alcohol-induced and other liver diseases was suggested in the study of acute liver failure (Liu et al. 2017).

용도

Dihydromyricetin has been used to study its effect on adipogenesis and glucose uptake in differentiated 3T3-L1 pre-adipocytes. It has also been used to study its antitumor activity against liver cancer cells.

정의

ChEBI: (+)-dihydromyricetin is an optically active form of dihydromyricetin having (2R,3R)-configuration. It has a role as a metabolite, an antioxidant and an antineoplastic agent. It is a secondary alpha-hydroxy ketone and a dihydromyricetin. It is an enantiomer of a (-)-dihydromyricetin.

다이하이드로미리세틴 준비 용품 및 원자재

원자재

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다이하이드로미리세틴 공급 업체

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