DICLOFENAC-D4

DICLOFENAC-D4 구조식 이미지
카스 번호:
153466-65-0
상품명:
DICLOFENAC-D4
동의어(영문):
D4-Diclofenac;DICLOFENAC-D4;[2H4]-Diclofenac;Diclofenac-D4 (Major);DICLOFENAC-D4 (PHENYL-D4);2-((2,6-Dichlorophenyl)aminobenzeneacetic Acid-d4,;2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]aceticaci;2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]acetic acid;Diclofenac D4Q: What is Diclofenac D4 Q: What is the CAS Number of Diclofenac D4 Q: What is the storage condition of Diclofenac D4 Q: What are the applications of Diclofenac D4
CBNumber:
CB1677920
분자식:
C14H11Cl2NO2
포뮬러 무게:
296.15
MOL 파일:
153466-65-0.mol

DICLOFENAC-D4 속성

녹는점
157-159°C
저장 조건
-20°C Freezer
용해도
DMSO: 35 mg/ml,Ethanol: 35 mg/ml,PBS (pH 7.2): 6 mg/ml
물리적 상태
고체
수용성
Water: 50 mg/ml
CAS 데이터베이스
153466-65-0
안전
  • 위험 및 안전 성명
그림문자(GHS): GHS hazard pictogramsGHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
NFPA 704
0
2 0

DICLOFENAC-D4 C화학적 특성, 용도, 생산

개요

Diclofenac-d4 is intended for use as an internal standard for the quantification of diclofenac (Item Nos. 70680 | 22983) by GC- or LC-MS. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.9-2.7 and 1.5-20 μM, for human COX-1 and COX-2, respectively). It is also an active metabolite of diclofenac methyl ester and diclofenac amide . Diclofenac inhibits release of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) induced by A23187 in isolated rat peritoneal neutrophils and macrophages (IC50s = 60 and 10 μM, respectively). Transdermal administration of diclofenac inhibits carrageenan-induced paw edema in rats. Formulations containing diclofenac have been used in the treatment of pain associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

화학적 성질

Off-White Crystalline Solid

용도

Labeled Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. 92% overall isotopic purity. A representative lot was 75% d4, 23% d3 and 2 % d2

DICLOFENAC-D4 준비 용품 및 원자재

원자재

준비 용품


DICLOFENAC-D4 공급 업체

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Hubei Jusheng Technology Co.,Ltd.
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Aladdin Scientific
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Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 18521732826;
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Cato Research Chemicals Inc. 020-81960175
min.he@cato-chem.com China 1958 55
ChemStrong Scientific Co.,Ltd 0755-66853366 13670046396
sales@chem-strong.com China 17982 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656
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