오르시놀
|
|
오르시놀 속성
- 녹는점
- 106-112 °C(lit.)
- 끓는 점
- 290 °C
- 밀도
- 1.2900
- 굴절률
- 1.4922 (estimate)
- 인화점
- 159 °C
- 저장 조건
- Store at <= 20°C.
- 용해도
- 80g/L
- 물리적 상태
- 결정질 분말 또는 결정
- 산도 계수 (pKa)
- 9.56±0.10(Predicted)
- 색상
- 분홍빛 회색에서 분홍빛 갈색까지
- 감도
- Air Sensitive
- Merck
- 14,6864
- BRN
- 1071903
- 안정성
- 흡습성
- InChIKey
- OIPPWFOQEKKFEE-UHFFFAOYSA-N
- LogP
- 1.221 (est)
- CAS 데이터베이스
- 504-15-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 22-36/37/38-41-37/38-20/21/22 | ||
안전지침서 | 22-26-36-37/39 | ||
유엔번호(UN No.) | 2811 | ||
WGK 독일 | 3 | ||
RTECS 번호 | VH2100000 | ||
TSCA | Yes | ||
포장분류 | III | ||
HS 번호 | 29072900 | ||
독성 | LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 5000 mg/kg | ||
기존화학 물질 | KE-23458 |
오르시놀 C화학적 특성, 용도, 생산
화학적 성질
pink-grey to pink-brown powder or crystals.용도
Orcinol can be used to synthesize:Orcinol-containing azacryptands for use in optical amplifiers and light-emitting devices.
Ternary co-crystal with 4,4′-bipyridine.
Low-density carbon aerogels in the presence of formaldehyde.
PEG-orcinol coumarins with potent tyrosinase inhibitory activity.
주요 응용
Orcinol is found in many lichen species and It is used as an analytical reagent for pentoses, lignin, beet sugar, saccharoses, arabinose, and diastase. The orcinol assay was used for the direct assay of the number of glycolipids presents in the sample. The orcinol reagent was prepared by adding concentrated sulphuric acid, H2SO4 (98% w/w) and 0.19% orcinol (3,5-dihydroxytoluene) to distilled water.정의
ChEBI: Orcinol is a 5-alkylresorcinol in which the alkyl group is specified as methyl. It has a role as an Aspergillus metabolite. It is a 5-alkylresorcinol and a dihydroxytoluene.제조 방법
Orcinol has been isolated from numerous lichen fungi (Robiquet, 1829) and can be synthesized by decarboxylation of orsellinic acid in Umbilicaria papulosa and Gliocladium roseum (Pettersson, 1965; Mosbach and Ehrensvard, 1966).Orcinol was first prepared by dehydroacetic acid, a conversion that involved ring-opening of the pyrone to a triketone. This early experiment helped establish the rich condensation chemistry of polyketides. It can be obtained by fusing extract of aloes with potash, followed by acidification.
US3865884A: Preparation of orcinol
생물학적 활성
Orcinol is a compound obtained from DHA which can mimic the biogenetic synthesis of phenolic compounds.Orcinol is a polyketide synthase-derived phenol that has been found in F. graminearum and has diverse biological activities. It scavenges DPPH radicals (IC50 = 2.93 mM). Orcinol (2.5 and 5 mg/kg) increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity. It has also been used in the colorimetric detection of carbohydrates.
Safety Profile
Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion and intraperitoneal routes. Mildly toxic by skin contact. When heated to decomposition it emits acrid smoke and irritating fumes.Purification Methods
Crystallise orcinol from CHCl3/*benzene (2:3). See hydrate in previous entry. [Beilstein 6 H 882, 6 IV 5892.]오르시놀 준비 용품 및 원자재
원자재
준비 용품
오르시놀 공급 업체
글로벌( 441)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 |
sales@anbuchem.com | China | 3000 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7845 | 58 |
Xiamen Work-For-World Medicine Co.,Ltd. | +undefined15921822462 |
keqingyong@wfwmed.com | China | 193 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 |
bj1@bj-chem.com | China | 298 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |