테트라시클린 수화염화물
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테트라시클린 수화염화물 속성
- 녹는점
- 220-223 °C(lit.)
- 알파
- -252 º (c=0.5, H2O)
- 굴절률
- -253 ° (C=0.5, 0.1mol/L HCl)
- 저장 조건
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- 용해도
- H2O: 원액으로 10 mg/mL. 원액은 여과하여 멸균하고 −20°C에 보관해야 합니다. 37°C에서 4일 동안 안정합니다.
- 물리적 상태
- 가루
- 색상
- 희미한 노란색에서 노란색까지
- 수소이온지수(pH)
- pH(10g/l, 25℃) : 1.8～3.0
- optical activity
- [α]/D -255 to 240° (Specific rotation )
- 수용성
- 50g/L
- 감도
- Air & Light Sensitive
- Merck
- 14,9196
- BRN
- 3844873
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- InChIKey
- XMEVHPAGJVLHIG-FMZCEJRJSA-N
- CAS 데이터베이스
- 64-75-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-20/21/22 | ||
| 안전지침서 | 26-36 | ||
| 유엔번호(UN No.) | UN 3077 9 / PGIII | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | QI9100000 | ||
| F 고인화성물질 | 8-10-23 | ||
| TSCA | Yes | ||
| 위험 등급 | 3 | ||
| HS 번호 | 29413000 | ||
| 독성 | LD50 orally in rats: 6443 mg/kg (Goldenthal) | ||
| 기존화학 물질 | KE-11172 |
테트라시클린 수화염화물 C화학적 특성, 용도, 생산
개요
Tetracycline is a broad-화학적 성질
Yellow crystalline powder용도
Tetracycline hydrochloride is a salt prepared from tetracycline taking advantage of the basic dimethylamino group which protonates and readily forms the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Tetracycline hydrochloride has broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-unit,s blocking protein synthesis.일반 설명
Crystals or fine bright yellow powder. pH of 2% aqueous solution: 2.1 - 2.3.공기와 물의 반응
Water soluble.반응 프로필
Tetracycline hydrochloride is acidic. Reacts with strong oxidizing agents .화재위험
Flash point data concerning Tetracycline hydrochloride are not available, however, Tetracycline hydrochloride is probably combustible.Safety Profile
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects: change in taste function. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also TETRACYCLINE.Purification Methods
The hydrochloride is recrystallised from MeOH/n-BuOH or n-BuOH/HCl. It is insoluble in Et2O and pet ether. It has UV max at 270 and 366nm in MeOH. [Gottstein et al. J Am Chem Soc 81 1198 1959, Conover et al. J Am Chem Soc 84 3222 1962, Stephen et al. J Am Chem Soc 78 4155 1956, Beilstein 14 IV 2627.]테트라시클린 수화염화물 준비 용품 및 원자재
원자재
(1S,2R)-1,2-Dihydroxycyclohexa-3,5-diene-1-carboxylic acid
5-Isoxazolemethanamine, 3-bromo-N,N-dimethyl-
Naphth[2,3-d]isoxazol-4(4aH)-one, 9-(dimethylamino)-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,8,8a,9-tetrahydro-4a-hydroxy-3-(phenylmethoxy)-, (4aS,5R,8aS,9S)-
Naphth[2,3-d]isoxazol-4(4aH)-one, 9-(dimethylamino)-5,8,8a,9-tetrahydro-4a,5-dihydroxy-3-(phenylmethoxy)-, (4aS,5R,8aS,9S)-
Naphth[2,3-d]isoxazole-4,5(4aH,8H)-dione, 9-(dimethylamino)-8a,9-dihydro-4a-hydroxy-3-(phenylmethoxy)-, (4aS,8aS,9S)-
테트라사이클린
준비 용품
테트라시클린 수화염화물 공급 업체
글로벌( 541)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 |
info@fortunachem.com | China | 5985 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12453 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 |
Sara@xmwonderfulbio.com | China | 305 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 |
sales@ichemie.com | China | 985 | 58 |
| Shanghai Affida new material science and technology center | +undefined15081010295 |
2691956269@qq.com | China | 359 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +86-13474506593 +86-13474506593 |
sarah@tnjone.com | China | 794 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9352 | 55 |
테트라시클린 수화염화물 관련 검색:
염산 옥시테트라사이클린 3-(디메틸아미노)프로필아민 클로르테트라사이클린 테트라사이클린 테트라시클린 수화염화물
Tetramisole hydrochloride
Minocycline
Topotecan hydrochloride
Clomocycline
Chlorothiazide
Trichlormethiazide
2-Naphthacenecarboxamide, N-[[4-[[(aminoiminomethyl)amino]iminomethyl]-1-piperazinyl]methyl]-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, dihydrochloride, [4S-(4alpha,4aalpha,5aalpha,6bet
Tetracycline hydrochloride BP2001/BP2002/USP26
Tetracycline, HCl, Cell Culture Tested
OXYTETRACYCLINE HYDROCHLORIDE IMP. B (EP) AS HYDROCHLORIDE: TETRACYCLINE HYDROCHLORIDE MM(CRM STANDARD)
Tetracycline HCl Eur.Pharm.
Tetracycline HCL BP98/USP24/EP97
{ TETRACYCLINE HCL (ANTIBIO