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다이소듐엔에이디에이치

다이소듐엔에이디에이치
다이소듐엔에이디에이치 구조식 이미지
카스 번호:
606-68-8
한글명:
다이소듐엔에이디에이치
동의어(한글):
다이소듐엔에이디에이치
상품명:
beta-Nicotinamide adenine dinucleotide disodium salt
동의어(영문):
NADH;DPNH;ENADA;NADH2;N 8129;NADH-NA2;NADH 2Na;DPNH2-NA2;DPNH, NA2;Co I reduced
CBNumber:
CB1709159
분자식:
C21H27N7Na2O14P2
포뮬러 무게:
709.4
MOL 파일:
606-68-8.mol

다이소듐엔에이디에이치 속성

녹는점
140-142°C
저장 조건
2-8°C
용해도
H2O: 50 mg/mL, clear to nearly clear, yellow
물리적 상태
Powder
색상
Yellow
수소이온지수(pH)
7.5 (100mg/mL in water, ±0.5)
수용성
soluble
BRN
5230241
안정성
Stable. Incompatible with strong oxidizing agents.
InChIKey
QRGNQKGQENGQSE-WUEGHLCSSA-L
CAS 데이터베이스
606-68-8
EPA
Adenosine 5'-(trihydrogen diphosphate), P'.fwdarw.5'-ester with 1,4-dihydro-1-.beta.-D-ribofuranosyl- 3-pyridinecarboxamide, disodium salt(606-68-8)

안전

위험품 표기 Xn
위험 카페고리 넘버 23/24/25-36/37/38-39/23/24/25-40-22
안전지침서 26-36/37/39-45-24/25-36/37
WGK 독일 3
F 고인화성물질 3-10-23
TSCA Yes
HS 번호 29349990

다이소듐엔에이디에이치 MSDS


beta-Nicotinamide adenine dinucleotide disodium salt

다이소듐엔에이디에이치 C화학적 특성, 용도, 생산

화학적 성질

beige powder

용도

One of the biologically active forms of nicotinic acid. Serves as a coenzyme of hydrogenases and dehydrogenases. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen d onor in the respiratory chain. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions. Occurs in 2 forms, α-NAD and β-NAD, distinguished by the configura tion of the ribosyl nicotinamide linkage. Only the β-anomer is bioactive.

정의

A dehydrogenase complex that is the reduced formof NAD.

Purification Methods

This coenzyme is available in high purity, and it is advisable to buy a fresh preparation rather than to purify an old sample as purification will invariably lead to a more impure sample contaminated with the oxidised form (NAD). It has UV max at 340nm ( 6,200 M-1cm-1) at which wavelength the oxidised form NAD has no absorption. At 340nm a 0.161mM solution in a 1cm (pathlength) cell has an absorbance of 1.0 unit. The purity is best checked by the ratio A280nm/A340nm ~2.1, a value which increases as oxidation proceeds. The dry powder is stable indefinitely at -20o. Solutions in aqueous buffers at pH ~7 are stable for extended periods at -20o and for at least 8hours at 0o, but are oxidised more rapidly at 4o in a cold room (e.g. almost completely oxidised overnight at 4o). [UV: Drabkin J Biol Chem 175 563 1945, Fluorescence: Boyer & Thorell Acta Chem Scand 10 447 1956, Redox: Rodkey J Biol Chem 234 188 1959, Schlenk in The Enzymes 2 250, 268 1951, Kaplan in The Enzymes 3 105, 112 1960.] Deuterated NADH, i.e. NADD, has been purified through the anion exchange resin AG-1 x 8 (100-200 mesh, formate form) and through a Bio-Gel P-2 column. [Viola et al. Anal Biochem 96 334 1979, Beilstein 26 III/IV 3639.]

다이소듐엔에이디에이치 준비 용품 및 원자재

원자재

준비 용품


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