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NS-398

NS-398 구조식 이미지

카스 번호:: 123653-11-2

상품명:: NS-398

동의어(영문):: NS NS;NS-398;CS-2231;NS-398 98%;Taisho NS 398;NS-398 (NS 398;NS-398 USP/EP/BP;NS-398 - CAS 123653-11-2 - Calbiochem;Inhibitor,inhibit,NS-398,NS 398,COX,Cyclooxygenase;N-[2-(cyclohexoxy)-4-nitro-phenyl]methanesulfonamide

CBNumber:: CB1754593

분자식:: C13H18N2O5S

포뮬러 무게:: 314.36

MOL 파일:: 123653-11-2.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 144

NS-398 속성

녹는점: 124-126 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))

끓는 점: 490.6±55.0 °C(Predicted)

밀도: 1.377±0.06 g/cm3(Predicted)

RTECS 번호: PB0473500

저장 조건: Sealed in dry,Room Temperature

용해도: DMSO: >5mg/mL

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 6.33±0.10(Predicted)

색상: 회백색

안전

안전지침서	22-24/25
WGK 독일	3
HS 번호	2935.90.9500

NS-398 C화학적 특성, 용도, 생산

개요

NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC₅₀ values for human recombinant COX-1 and -2 are 75 and 1.77 μM, respectively. The IC₅₀ values for ovine COX-1 and -2 are 220 and 0.15 μM, respectively.

용도

NS-398 is a selective Cox-2 inhibitor neuroprotective agent.

정의

ChEBI: A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

생물학적 활성

Selective cyclooxygenase-2 inhibitor (IC 50 values are 3.8 and > 100 μ M for COX-2 and COX-1 respectively). Induces apoptosis in colorectal tumor cells and elevates COX-2 protein expression in vitro . Orally active and non-ulcerogenic analgesic and anti-inflammatory in vivo .

NS-398 준비 용품 및 원자재

원자재

준비 용품

글리옥살 아크릴아마이드

NS-398 공급 업체

글로벌( 144)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	sales03@chemcn.cn	China	951	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29474	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503259 +86-19930503259	cherry@crovellbio.com	China	18458	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58

NS-398 관련 검색:

칼륨 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-헵타데카플루오로-1- 옥탄술폰산 펜타나트륨 펜텐산 CALPHOSTIN C Trypsin inhibitor AG 18 AG 490 TYRPHOSTIN A25 Roscovitine Potassium clavulanate Ancymidol NS-398 3-ISOPROPOXYANILINE 4-NITRO METHANESULFONANILIDE 4-nitro-o-phenetidine N-(2-METHOXY-4-NITRO-PHENYL)-METHANESULFONAMIDE 4-NITRO-2-PROPOXY-PHENYLAMINE NS-398 (N-(2-Cyclohexyloxy-4-nitrophenyl) -Methanesulfonamide) Methanesulfonamide, N-(2-ethoxyphenyl)- (9CI)