Naratriptan

Naratriptan 구조식 이미지
카스 번호:
121679-13-8
상품명:
Naratriptan
동의어(영문):
Naratriptan;Naratriptan1;Naratriptane;Naratriptan(Amerge);AMERGE; NARAMIG; GR-85548A;N-methyl-3-(1-methyl-4-piperidinyl)-1H-Indole-5-ethanesulfonamide;N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide;N-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide;Inhibitor,GR-85548A,5-hydroxytryptamine Receptor,inhibit,Serotonin Receptor,5-HT Receptor,Naratriptan;NaratriptanQ: What is Naratriptan Q: What is the CAS Number of Naratriptan Q: What is the storage condition of Naratriptan
CBNumber:
CB1874790
분자식:
C17H25N3O2S
포뮬러 무게:
335.46
MOL 파일:
121679-13-8.mol

Naratriptan 속성

녹는점
170-171°
끓는 점
541.3±60.0 °C(Predicted)
밀도
1.227±0.06 g/cm3(Predicted)
산도 계수 (pKa)
11.52±0.40(Predicted)

안전

Naratriptan C화학적 특성, 용도, 생산

용도

Naratriptan is a triptan drug that is used for the treatment of migraine headaches.

일반 설명

Naratriptan, the third triptan approved in 1998, is one of themost lipophilic triptans marketed to date. It has a much improvedbioavailability (63% in men and 74% in women), agreater affinity for 5-HT1B/1D receptors (3–6 times), and alower recurrence rate than sumatriptan because of its muchlonger elimination half-life. Naratritan also has a favorableCNS side effect profile when compared with sumatriptanor zolmitriptan because of its metabolic stability,thereby lacking a N-demethylated active metabolite and asignificant renal excretion ( 70% of naratriptan is excretedunchanged and the rest of the administered dose is degradedvia several CYP isozymes).

Naratriptan 준비 용품 및 원자재

원자재

준비 용품


Naratriptan 공급 업체

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