(R)-(-)-alpha-Methoxyphenylacetic acid
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(R)-(-)-alpha-Methoxyphenylacetic acid 속성
- 녹는점
- 66-68 °C(lit.)
- 끓는 점
- 164-166°C 18mm
- 알파
- -160.4 º (C=1, MEOH)
- 밀도
- 1.1708 (rough estimate)
- 굴절률
- -147 ° (C=0.5, EtOH)
- 인화점
- 164-166°C/18mm
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름, 에탄올, 메탄올에 용해됨
- 물리적 상태
- 바늘 모양 또는 분말 모양의 결정체
- 산도 계수 (pKa)
- 3.10±0.10(Predicted)
- 색상
- 하얀색
- optical activity
- [α]20/D -150±3°, c = 0.5% in ethanol
- BRN
- 3589257
- CAS 데이터베이스
- 3966-32-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
(R)-(-)-alpha-Methoxyphenylacetic acid C화학적 특성, 용도, 생산
화학적 성질
white fine crystalline powder or needles용도
(R)-(-)-α-Methoxyphenylacetic Acid is a useful synthetic intermediate. It is used as a reactant in the synthesis of dopamine receptor agonists. It can also be used to prepare hydroxytriamides as potent γ-secretase inhibitors.일반 설명
(R)-(?)-α-Methoxyphenylacetic acid is a chiral derivatizating agent, which is employed for derivatizing enantiomers into diastereoisomers.Purification Methods
Purify the acids by recrystallising from *C6H6/pet ether (b 80-100o). [Neilson & Peters J Chem Soc 1519 1962, Weizmann et al. J Am Chem Soc 70 1153 1948, Pirie & Smith J Chem Soc 338 1932, NMR: Dale & Mosher J Am Chem Soc 9 5 512 1973, for resolution: Roy & Deslongchamps Can J Chem 63 651 1985, Trost et al. J Am Chem Soc 1 0 8 4974 1986.] The racemic mixture has m 72o, b 121-122o/0.4mm, 165o/18mm (from pet ether) [Braun et al. Chem Ber 6 3 2847 1930]. [Beilstein 10 IV 566.](R)-(-)-alpha-Methoxyphenylacetic acid 준비 용품 및 원자재
원자재
준비 용품
(R)-(-)-alpha-Methoxyphenylacetic acid 공급 업체
글로벌( 171)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15371 | 58 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 |
sales@fine-chemtech.com | CHINA | 885 | 55 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 |
contact@fuxinpharm.com | China | 10297 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 |
joe@yuhengpharm.com | CHINA | 21149 | 58 |