Malabaricone C

Malabaricone C 구조식 이미지
카스 번호:
63335-25-1
상품명:
Malabaricone C
동의어(영문):
Malabaricone C;1-(2,6-Dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)-1-nonanone;1-(2,6-dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)nonan-1-one;1-Nonanone, 1-(2,6-dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)-;lipid metabolism,Inhibitor,sphingomyelin synthase,SMS 1,diet,obesity,inhibit,Malabaricone C,SMS 2
CBNumber:
CB21120408
분자식:
C21H26O5
포뮬러 무게:
358.43
MOL 파일:
63335-25-1.mol

Malabaricone C 속성

저장 조건
Store at -20°C
용해도
DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
물리적 상태
결정성 고체

안전

Malabaricone C C화학적 특성, 용도, 생산

개요

Malabaricone C is a diarylnonanoid that has been found in Myristica and has diverse biological activities. It scavenges 59.9% of 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals when used at a concentration of 7 μg/ml. Malabaricone C is active against S. aureus, B. subtilis, and C. albicans in vitro (MICs = 2-32 μg/ml). It is cytotoxic to A549, HL-60, and MCF-7 cells (IC50s = 12.3, 46.1, and 10.8 μM, respectively). Malabaricone C inhibits sphingomyelin synthase 1 (SMS1) and SMS2 activity in cell lysates (IC50s = 3 and 1.5 μM, respectively). It decreases body weight gain, hepatic steatosis, and hepatic and plasma triglyceride levels in a mouse model of high-fat diet-induced obesity when administered at a dose of 0.1% in the diet.

정의

ChEBI: A natural product found in Myristica cinnamomea.

Malabaricone C 준비 용품 및 원자재

원자재

준비 용품


Malabaricone C 공급 업체

글로벌( 26)공급 업체
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Jiangsu Yongjian Pharmaceutical Co.,Ltd
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jessica.hu@chemieliva.com China 1418 60
Chengdu Push Bio-Technology Co., Ltd. 028-85370565-229 18080489829
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